Browsing Faculty of Health Sciences by Author "10922180 - Schutte, Aletta Elisabeth"
Now showing items 1-20 of 273
-
A 10-year follow-up study of demographic and cardiometabolic factors in HIV-infected South Africans
Phalane, Edith; Fourie, Carla Maria; Mels, Catharina Martha; Schutte, Aletta Elisabeth (Clinics Cardive Publishing, 2019)Objectives: Understanding of the interplay between human immunodeficiency virus (HIV) and cardiovascular disease, especially in Africa, is limited to evidence from longitudinal studies. Therefore the demographic profile ... -
2020 International Society of Hypertension global hypertension practice guidelines
Unger, Thomas; Schutte, Aletta E.; Borghi, Claudio; Charchar, Fadi; Khan, Nadia A. (AHA, 2020)Context and Purpose of This Guideline Statement of Remit To align with its mission to reduce the global burden of raised blood pressure (BP), the International Society of Hypertension (ISH) has developed worldwide ... -
2020 International Society of Hypertension global hypertension practice guidelines - lifestyle modification. Reply
Schutte, Aletta E.; Charchar, Fadi; Prabhakaran, Dorairaj (Wolters Kluwer, 2020)The 2020 ISH Global Hypertension Practice Guidelines [1] include a detailed list of lifestyle modifications with varying levels of evidence for the reduction of blood pressure and cardiovascular risk. We listed some novel ... -
24-Hour central blood pressure: reference values for healthy individuals. The international 24hour ambulatory aortic blood pressure consortium (I24ABC)
Weber, T.; Schutte, A.E.; Ware, L.; Protogerou, A.; Wassertheurer, S. (Wolters Kluwer, 2019)Objective: Central systolic blood pressure (cSBP) differs from peripheral SBP (pSBP) and may have higher prognostic relevance, but the normal values in ambulatory conditions are unknown. We present reference values for ... -
8-Oxo-7,8-dihydro-2’-deoxyguanosine, reactive oxygen species and ambulatory blood pressure in African and Caucasian men: the SABPA study
Mels, C.M.C.; Schutte, A.E.; Schutte, R.; Pretorius, P.J.; Smith, W.; Huisman, H.W.; Van der Westhuizen, F.H.; Fourie, C.M.T.; Van Rooyen, J.M.; Kruger, R.; Louw, R.; Malan, N.T.; Malan, L. (Taylor & Francis, 2014)Various studies indicate a relationship between increased oxidative stress and hypertension, resulting in increased DNA damage and consequent excretion of 8-oxo-7,8-dihydro-2’-deoxyguanosine (8-oxodG). The aim of this study ... -
A biomarker of tissue damage, lactate dehydrogenase, is associated with fibulin-1 and oxidative stress in blacks: the SAfrEIC study
Mokwatsi, Gontse G.; Schutte, Aletta E.; Kruger, Ruan (Taylor & Francis Ltd, 2016)Context: Extracellular matrix (ECM) remodeling and oxidative stress is present in hypertension and associated arterial stiffness, but little is known on the physiological link among lactate dehydrogenase (LDH), fibulin-1, ... -
A call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the Lancet Commission on hypertension
Olsen, Michael H.; Schutte, Aletta E.; Angell, Sonia Y.; Asma, Samira; Boutouyrie, Pierre (Elsevier Science Inc, 2016)Elevated blood pressure is the strongest modifiable risk factor for cardiovascular disease worldwide. Despite extensive knowledge about ways to prevent as well as to treat hypertension, the global incidence and prevalence ... -
A century of trends in adult human height
Bentham, James; Kruger, Herculina S.; Schutte, Aletta E.; Di Sesare, Maria; Stevens, Gretchen A. (eLife Sciences Publications Ltd, 2016)Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height ... -
The accuracy in measurement of blood pressure (AIM‐BP) collaborative: background and rationale
Padwal, Raj; Schutte, Aletta E.; Campbell, Norm R.C.; Weber, Michael A.; Lackland, Daniel (Wiley, 2019)Blood pressure (BP) measurement, a technique first described over a century ago, is an essential component of clinical care and critical for the detection and management of hypertension.1 Accordingly, the ramifications ... -
Adipokines and cardiometabolic function: how are they interlinked?
Schutte, Aletta Elisabeth; Huisman, Hugo Willem; Schutte, Rudolph; Van Rooyen, Johannes Marthinus; Malan, Leoné; Fourie, Catharina Maria Theresia; Malan, Nicolaas Theodor (Elsevier, 2010)Objective Adipokines contribute directly to the coexistence of insulin resistance and endothelial dysfunction. Most studies focus on a single adipokine. We therefore investigated the independent relationships of leptin, ... -
Adiposity and physical activity are related to heart rate variability: the African-PREDICT study
Köchli, Sabrina; Schutte, Aletta E.; Kruger, Ruan (Wiley, 2020)Background Physical inactivity contributes significantly to the development of obesity‐related cardiovascular disease. Adiposity may lead to reduced heart rate variability (HRV), whereas increased physical activity (PA) ... -
The African prospective study on the early detection and identification of cardiovascular disease and hypertension (African-PREDICT): design, recruitment and initial examination
Schutte, Aletta E.; Uys, Aletta S.; Burger, Adele; Mels, Catharina M.C.; Kruger, Ruan; Smith, Wayne; Fourie, Carla M.T.; Botha, Shani; Lammertyn, Leandi; Van Rooyen, Johannes M.; Gafane-Matemane, Lebo F.; Mokwatsi, Gontse G.; Breet, Yolandi; Kruger, H. Salome; Van Zyl, Tertia; Pieters, Marlien; Zandberg, Lizelle; Louw, Roan; Moss, Sarah J.; Huisman, Hugo W. (Sage, 2019)Background: Globally hypertension is stabilising, but in sub-Saharan Africa the incidence of hypertension remains on an increase. Although this might be attributed to poor healthcare and ineffective antihypertensive ... -
Alcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study
Smyth, Andrew; Teo, Koon K.; Rangarajan, Sumathy; O’Donnell, Martin; Schutte, Aletta E. (Elsevier, 2015)Background: Alcohol consumption is proposed to be the third most important modifi able risk factor for death and disability. However, alcohol consumption has been associated with both benefi ts and harms, and previous ... -
Alcohol intake, hypertension development and mortality in black South Africans
Zatu, Mandlenkosi C.; Van Rooyen, Johannes M.; Kruger, Annamarie; Schutte, Aletta E. (Sage Publishing, 2016)Background: Excessive alcohol intake is a risk factor for cardiovascular disease (CVD) and predicts cardiovascular and all-cause mortality. We determined which alcohol marker (self-reported alcohol intake, gamma-glutamy ... -
Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016
Griswold, Max G.; Oyekale, Abayomi Samuel; Schutte, Aletta Elisabeth; Fullman, Nancy; Hawley, Caitlin (Elsevier, 2018)Background Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. ... -
Aldosterone and renin in relation to surrogate measures of sympathetic activity: the SABPA study
Gafane-Matemane, Lebo F.; Van Rooyen, Johannes M.; Schutte, Rudolph; Schutte, Aletta E. (Clinics Cardive Publishing, 2019)Introduction: Hypertension, particularly in black populations, is often accompanied by augmented sympathetic nervous system activity and suppressed renin activity, indicative of possible blood pressure (BP) dysregulation. ... -
Are behavioural risk factors to be blamed for the conversion from optimal blood pressure to hypertensive status in black South Africans? A 5-year prospective study
Schutte, Rudolph; Schutte, Aletta E.; Huisman, Hugo W.; Van Rooyen, Johannes M.; Fourie, Carla M.T. (Oxford University Press, 2012)Background Longitudinal cohort studies in sub-Saharan Africa are urgently needed to understand cardiovascular disease development. We, therefore, explored health behaviours and conventional risk factors of African individuals ... -
Are the American Heart Association/American College of Cardiology high blood pressure guidelines fit for global purpose? Thoughts from the International Society of Hypertension
Poulter, Neil R.; Schutte, Aletta E.; Castillo, Rafael; Charchar, Fadi J.; Schlaich, Markus P. (American Heart Association, 2018)In 2017, the American College of Cardiology (ACC), the American Heart Association (AHA), and 9 other American societies released guidelines for the prevention, detection, evaluation, and management of high blood pressure ... -
Arterial stiffness profiles: investigating various sections of the arterial tree of African and caucasian people
Huisman, Hugo Willem; Malan, Nicolaas Theodor; Schutte, Aletta Elisabeth; Schutte, Rudolph; Van Rooyen, Johannes Marthinus; Malan, Leoné; Reimann, Manja (Informa healthcare, 2011)In Africans, arterial stiffness progression seems more pronounced compared to Caucasians. We compared the arterial stiffness profiles of different age groups and focused on muscular arteries and two more central arterial ... -
Arterial stiffness, ambulatory blood pressure and low-grade albuminuria in non-diabetic African and caucasian men: the SABPA study
Schutte, Rudolph; Schutte, Aletta E.; Huisman, Hugo W.; Glyn, Matthew C.P.; Van Rooyen, Johannes M.; Malan, Nicolaas T.; Fourie, Carla M.T.; Malan, Leoné (Nature Publishing Group, 2011)Recent evidence suggests that low-grade urinary albumin excretion is a marker of early general attenuation of vascular function, but studies are limited to Caucasian population groups. We compared low-grade urinary albumin ...