Browsing Faculty of Health Sciences by Author "20030223 - Uys, Aletta Sophia"
Now showing items 1-7 of 7
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The African prospective study on the early detection and identification of cardiovascular disease and hypertension (African-PREDICT): design, recruitment and initial examination
Schutte, Aletta E.; Uys, Aletta S.; Burger, Adele; Mels, Catharina M.C.; Kruger, Ruan; Smith, Wayne; Fourie, Carla M.T.; Botha, Shani; Lammertyn, Leandi; Van Rooyen, Johannes M.; Gafane-Matemane, Lebo F.; Mokwatsi, Gontse G.; Breet, Yolandi; Kruger, H. Salome; Van Zyl, Tertia; Pieters, Marlien; Zandberg, Lizelle; Louw, Roan; Moss, Sarah J.; Huisman, Hugo W. (Sage, 2019)Background: Globally hypertension is stabilising, but in sub-Saharan Africa the incidence of hypertension remains on an increase. Although this might be attributed to poor healthcare and ineffective antihypertensive ... -
Assessing tobacco use in an African population: serum and urine cotinine cut-offs from South Africa
Ware, Lisa J.; Kruger, Ruan; Breet, Yolandi; Van Rooyen, Johannes; Huisman, Hugo; Botha, Shani; Uys, Aletta S.; Schutte, Aletta E. (Elsevier, 2019)Background Cotinine, a nicotine metabolite, is used to measure tobacco use and exposure, but recommended cut-offs to differentiate tobacco users from those exposed through the environment range from 3 to 58 ng/ml in serum, ... -
Attenuated brain-derived neurotrophic factor and hypertrophic remodelling: the SABPA study
Smith, A.J.; Malan, L.; Uys, A.S.; Malan, N.T.; Harvey, B.H. (Springer Nature, 2015)Brain-derived neurotrophic factor (BDNF) has been linked to neurological pathologies, but its role in cardiometabolic disturbances is limited. We aimed to assess the association between serum BDNF levels and structural ... -
Attenuated NOx responses and myocardial ischemia, a possible risk for structural vascular disease in African men: the SABPA study
Uys, A.S.; Malan, L.; Van Rooyen, J.M.; Steyn, H.S.; Reimann, M. (Nature Publishing Group, 2014)Chronically elevated blood pressure has been associated with impaired NO-mediated vasodilation and structural vascular disease risk. This study aimed to determine whether significant associations exist regarding NO metabolite ... -
Evaluation of waist-to-height ratio to predict 5 year cardiometabolic risk in sub-Saharan African adults
Ware, L.J.; Kruger, H.S.; Kruger, I.M.; Greeff, M.; Fourie, C.M.T.; Huisman, H.W.; Scheepers, J.D.W.; Uys, A.S.; Kruger, R.; Van Rooyen, J.M.; Schutte, R.; Schutte, A.E. (Open Access, 2014)Background and aims Simple, low-cost central obesity measures may help identify individuals with increased cardiometabolic disease risk, although it is unclear which measures perform best in African adults. We aimed to: ... -
Low grade inflammation and ECG left ventricular hypertrophy in urban African males: the SABPA study
Van der Walt, Carel; Malan, Leoné; Uys, Aletta S.; Malan, Nicolaas T. (Elsevier, 2013)BACKGROUND: Hypertension and vascular hyperresponsiveness have been associated with structural wall abnormalities in black Africans. Whether low grade inflammation would have an additive effect is uncertain. Therefore, ... -
Nocturnal blood pressure, 3-methoxy-4-hydroxyphenylglycol and carotidIntima-media thickness: the SABPA Study
Uys, Aletta S.; Malan, Leoné; Van Rooyen, Johannes M.; Steyn, Hendrik S.; Ziemssen, Tjalf; Reimann, Manja (Elsevier, 2013)Background: Research demonstrated a significant relationship between elevated nocturnal blood pressure and sym-pathetic hyperactivity. The study aimed to investigate possible associations between norepinephrine ...