Browsing Faculty of Health Sciences by Author "21649987 - Du Toit, Trizel"
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Combining chemical permeation enhancers for synergistic effects
Du Toit, Trizel; Malan, Maides M.; Lemmer, Hendrik J.R.; Gouws, Chrisna; Aucamp, Marique E.; Breytenbach, Wilma J.; Hamman, Josias H. (Springer, 2016)Currently, macromolecular drugs such as proteins are mainly administered by means of injections due to their low intestinal epithelial permeability and poor stability in the gastrointestinal tract. This study ... -
Novel non-invasive protein and peptide drug delivery approaches
Wallis, Lonette; Kleynhans, Elmarie; Du Toit, Trizel; Gouws, Chrisna; Steyn, Dewald; Steenekamp, Jan; Viljoen, Joe; Hamman, Josias (Bentham Science, 2014)Protein and peptide based therapeutics are typically administered by injection due to their poor uptake when administered via enteral routes of drug administration. Unfortunately, chronic administration of these drugs ...