Browsing Faculty of Health Sciences by Author "Combrinck, Sandra"
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In vitro permeation of mesembrine alkaloids from Sceletium tortuosum across porcine buccal, sublingual, and intestinal mucosa
Shikanga, Emmanuel A.; Hamman, Josias H.; Chen, Weiyang; Combrinck, Sandra; Gericke, Nigel (Thieme, 2012)Sceletium tortuosum is an indigenous South African plant that has traditionally been used for its mood-enhancing properties. Recently, products containing S. tortuosum have become increasingly popular and are commonly ... -
Isolation and in vitro permeation of phenylpropylamino alkaloids from Khat (Catha edulis) across oral and intestinal mucosal tissues
Atlabachew, Minaleshewa; Hamman, Josias H.; Gouws, Chrisna; Combrinck, Sandra; Viljoen, Alvaro M. (Elsevier, 2016)Ethnopharmacological relevance: Khat, the leaves of Catha edulis, is used as a “natural amphetamine-like” stimulant in eastern and southern Africa, as well as in the Arabian Peninsula. Leaves are masticated to elicit a ... -
Potential herb-drug pharmacokinetic interactions between African Wild Olive leaf extract and selected antihypertensive drugs
Mmopele, Katlego; Hamman, Josias; Willers, Clarissa; Combrinck, Sandra; Chen, Weiyang (Thieme, 2018)The African wild olive (Olea europaea subsp. africana) is traditionally used as a hypotensive agent. Herb-drug interactions may result from the concurrent use of herbal medicines and conventional prescription drugs. This ...