Browsing Faculty of Health Sciences by Author "Gravestock, David"
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Design, synthesis and biological evaluation of 6-aryl-1,6-dihydro-1,3,5-triazine-2,4-diamines as antiplasmodial antifolates
Lourens, Anna C.U.; Gravestock, David; Van Zyl, Robyn L.; Hoppe, Heinrich C.; Kolesnikova, Natasha (RSC, 2016)The design, synthesis and biological evaluation of a series of 6-aryl-1,6-dihydro-1,3,5-triazine-2,4- diamines is described. These compounds exhibited in vitro antiplasmodial activity in the low nanomolar range against ...