Browsing Faculty of Health Sciences by Author "Grobler, A."

Now showing items 1-3 of 3

    • Modeling nanoparticle delivery of TB drugs to granulomas 

      Grobler, A.; Viljoen, H.J.; Perez Sierra, Z. (Elsevier, 2016)
      Tuberculosis, which typically presents as a pulmonary disease, has a complex pathology. The primary site of infection, the Ghon focus, recruits immune cells and a granuloma forms. At earlier stages the granuloma is still ...

    • Poly (D,L-lactide-co-glycolide) nanoparticles: uptake by epithelial cells and cytotoxicity 

      Nkabinde, L.A.; Grobler, A.; Hamman, J.H.; Shoba-Zikhali, L.N.N.; Semete-Makokotlela, B. (Budapest University of Technology, 2014)
      Nanoparticles as drug delivery systems offer benefits such as protection of the encapsulated drug against degradation, site-specific targeting and prolonged blood circulation times. The aim of this study was to investigate ...

    • Topical and transdermal delivery of L-carnitine 

      Fox, L.T.; Gerber, M.; Grobler, A.; Du Preez, J.L.; Du Plessis, J. (Karger, 2011)
      Background: The two types of skin aging (intrinsic and extrinsic) share important molecular features, while having distinct differences on the macromolecular level: both lead to increased production of reactive oxygen ...