Browsing Faculty of Health Sciences by Subject "Kinetics"
Now showing items 1-4 of 4
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Characterization of polymorph transformations that decrease the stability of tablets containing the who essential drug mebendazole
(Elsevier, 2010)This study investigated the influence of moisture and heat on the stability of mebendazole polymorph C in tablets. The polymorphic forms of mebendazole display significant differences in solubility and therapeutic efficacy ... -
Preparation and transformation of true nifedipine polymorphs: investigated with differential scanning calorimetry and X-Ray diffraction pattern fitting methods
(Elsevier, 2011)The amorphous → metastable and metastable → stable crystalline phase transitions of nifedipine and their relationship with polymorph composition during storage at controlled temperature/humidity conditions were investigated. ... -
Rapid cell lysis and DNA capture in a lysis microreactor
(Elsevier, 2012)In clinical diagnostics, the detection and identification of bacterial organisms based on the analysis of their nucleic acids require cell lysis and DNA extraction from clinical samples. A lysis microreactor (LMR) has been ... -
Solid state concerns during drug discovery and development: thermodynamic and kinetic aspects of crystal polymorphism and the special cases of concomitant polymorphs, co-crystals and glasses
(Bentham Science, 2017)During drug discovery and development the thermodynamics and kinetics of crystal form transitions must be studied and the fundamental properties of polymorphs must be identified. However, despite the accumulation of knowledge ...