Browsing Faculty of Health Sciences by Author "Lubbe, Martie S."
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Advances in cancer therapeutics and patient access to new drugs
Dranitsaris, George; Lubbe, Martie S.; Truter, Ilse; Amir, Eitan; Evans, William (Springer, 2011)Globally, there are approximately 7.4 million cancer deaths annually, approximately 13% of deaths from all causes. Cancer is a disease of older people and, as the population ages over the next 10–20 years, we can expect ... -
Anti-epileptic prescribing patterns in the South African private health sector (2008-2013)
Jacobs, Karen; Julyan, Marlene; Lubbe, Martie S.; Burger, Johanita R.; Cockeran, Marike (Taylor & Francis, 2016)Background: Little is known about longitudinal prescribing practices for anti-epileptic drugs (AEDs) in South Africa. The prescribing patterns and associated direct medicine costs of AEDs in the private ... -
The application of pharmacoeconomic modelling to estimate a value-based price for new cancer drugs
Dranitsaris, George; Lubbe, Martie S.; Truter, Ilse; Cottrell, Wayne; Spirovski, Biljana (Wiley, 2010)Rationale, aims and objectives Value‐based pricing has recently been discussed by international bodies as a means to estimate a drug price that is linked to the benefits it offers patients and society. The World Health ... -
Client perceptions of interaction with community pharmacists in the Nelson Mandela Metropole
Knoesen, Brent C.; Lubbe, Martie S.; Truter, Ilse (Taylor & Francis, 2017)Communication plays an important role in health care professions, such as pharmacy, which is an information-driven profession in which community pharmacists are embedded. They are responsible for ensuring patient-centred ... -
Coexisting conditions among children and adolescents with cancer in a section of the South African private health sector: perspectives from drug utilization data
Otoo, Marianne N.; Lubbe, Martie S.; Steyn, Hanlie; Burger, Johanita R. (Atlantis Press, 2020)Coexisting conditions are relatively common in children with cancer, however, there is a paucity of information on the prevalence of coexisting conditions in children with cancer in South Africa. This cross-sectional study ... -
Determining potential drug-drug interactions between lopinavir/ritonavir and other antiretrovirals and prescribed daily doses in a section of the private health care sector in South Africa
Katende-Kyenda, Norah L.; Lubbe, Martie S.; Serfontein, Jan H.P.; Truter, Ilse (Academic Journals, 2013)Lopinavir/ritonavir forms part of the antiretroviral therapy for the treatment of human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS). The aim of this non-experimental, quantitative drug-utilization ... -
The development of a value based pricing index for new drugs in metastatic colorectal cancer
Dranitsaris, George; Lubbe, Martie S.; Truter, Ilse (Elsevier, 2011)Background Worldwide, prices for cancer drugs have been under downward pressure where several governments have mandated price cuts of branded products. A better alternative to government mandated price cuts would be to ... -
Factors influencing access to pharmaceutical services in underserviced areas of the West Rand District, Gauteng Province, South Africa
Sello, Ditonkana A.; Serfontein, Jan H.P.; Lubbe, Martie S.; Dambisya, Yoswa M. (AOSIS, 2012)The study examined demographic and socio-economic factors that may influence pharmaceutical services (PS) in underserviced communities of the West Rand District, Gauteng Province, South Africa. A quantitative survey was ... -
Further potential saving attributable to maximum generic substitution of antidepressants in South Africa: a retrospective analysis of medical claims
Van der Westhuizen, Elmarie; Burger, Johanita R.; Lubbe, Martie S.; Serfontein, Jan H.P. (AOSIS, 2010)The main objective of the study was to calculate potential cost savings that could have been generated by maximum generic substitution of antidepressants within the private health care sector of South Africa from 2004 ... -
The impact of HIV/AIDS on compliance with antidepressant treatment in major depressive disorder: a prospective study in a South African private healthcare cohort
Slabbert, Francois N.; Harvey, Brian H.; Brink, Christiaan B.; Lubbe, Martie S. (BioMed Central, 2015)Background: MDD and HIV/AIDS have a high prevalence worldwide with severe consequences for patients. In both conditions, compliance with treatment is key to successfully treat these disorders. In the current study, ... -
Improving patient access to cancer drugs in India: using economic modeling to estimate a more affordable drug cost based on measures of societal value
Dranitsaris, George; Lubbe, Martie S.; Truter, Ilse; Sriramanakoppa, Nitin N.; Mendonca, Vivian M. (Cambridge Univ Press, 2011)Background: Using multiples of India's per capita gross domestic product (GDP) as the threshold for economic value as suggested by the World Health Organization (WHO), decision analysis modeling was used to estimate a more ... -
Medicine possession ratio as proxy for adherence to antiepileptic drugs: prevalence, associations, and cost implications
Jacobs, Karen; Julyan, Marlene; Lubbe, Martie S.; Burger, Johanita R.; Cockeran, Marike (Dovepress, 2016)Objective: To determine the adherence status to antiepileptic drugs (AEDs) among epilepsy patients; to observe the association between adherence status and age, sex, active ingredient prescribed, treatment period, and ... -
Methylphenidate and atomoxetine prescribing trends in children in the Western Cape Province of South Africa, 2005-2013
Joubert, Liezl; Burger, Johanita R.; Lubbe, Martie S.; Cockeran, Marike; Truter, Ilse (AOSIS, 2018)Background: There is paucity of data on methylphenidate and atomoxetine prescribing patterns in South African children. Aim: To describe the prescribing trends of these agents in children residing in the Western Cape ... -
The potential market demand for biokinetics in the private health care sector of South Africa
Moss, Sarah J.; Lubbe, Martie S. (ASSAf, 2011)Objective. Biokinetics, a profession registered with the Health Professions Council of South Africa (HPCSA) address inter alia chronic diseases of lifestyle (CDL) with exercise as treatment modality. The purpose of this ... -
Prescribing patterns of medicine classified as 'antidepressants' in South African children and adolescents
Burger, Johanita R.; Van der Westhuizen, Elmarie; Lubbe, Martie S.; Serfontein, Jan H.P. (AOSIS, 2009)Die algemene doelstelling van hierdie studie was om die voorskrifpatrone van middels wat as 'antidepressante' geklassifiseer word (hierna verwys na as slegs antidepressante) wat vir kinders en adolessente in die Suid-Afrikaanse ... -
Prescribing patterns of non-steroidal anti-inflammatory drugs in chronic kidney disease patients in the South African private sector
Meuwesen, Willem P.; Du Plessis, Jesslee M.; Burger, Johanita R.; Lubbe, Martie S.; Cockeran, Marike (Springer, 2016)Background Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used pharmaceutical agents worldwide. NSAIDs are considered nephrotoxic and should therefore be used with caution or be avoided completely ... -
Public knowledge, attitudes and behaviour towards antibiotic usage in Windhoek, Namibia
Pereko, Dawn D.; Lubbe, Martie S.; Essack, Sabiha Y. (Taylor & Francis, 2015)Background: The development of antibiotic resistance is a globally recognised human health threat. Overuse of antibiotics is a major contributory factor to the development of resistance. As end users, the public play a ... -
Surveillance of antibiotic use in the private sector in Namibia using sales and claims data
Pereko, Dawn Dineo; Lubbe, Martie S.; Essack, Sabiha Y. (PKP, 2016)Introduction: Antibiotics are among the most commonly used therapeutic agents for humans globally, and their use has been associated with the development of resistance. The objective of this study was to identify sources ...