Browsing Faculty of Health Sciences by Subject "Methoxypoly(ethylene glycol) (MPEG)"
Now showing items 1-2 of 2
-
Synthesis and in vitro transdermal penetration of methoxypoly(ethylene glycol) carbonate derivatives of stavudine (3TC)
(Bentham Science, 2009)The objective of this study was to synthesize derivatives of the anti-HIV drug stavudine (d4T) with more favourable physicochemical properties for transdermal delivery in an effort to increase transdermal penetration of ... -
Synthesis of methodxypoly (ethylene glycol) carbonate prodrugs of zidovudine and penetration through human skin in vitro
(Wiley, 2009)The aim of this study was to synthesise a series of novel methoxypoly(ethylene glycol) carbonate prodrugs of the antiretroviral drug zidovudine (azidothymidine, AZT) in an attempt to enhance the physicochemical properties ...