Browsing Faculty of Health Sciences by Subject "PLGA nanoparticles"
Now showing items 1-4 of 4
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Functionalization of PLGA nanoparticles with 1,3-β-glucan enhances the intracellular pharmacokinetics of rifampicin in macrophages
(Springer, 2018)Purpose Mycobacterium tuberculosis which causes tuberculosis, is primarily resident within macrophages. 1,3-β-glucan has been proposed as a ligand to target drug loaded nanoparticles (NPs) to macrophages. In this study ... -
In vivo uptake and acute immune response to orally administered chitosan and PEG coated PLGA nanoparticles
(Elsevier, 2010)Nanoparticulate drug delivery systems offer great promise in addressing challenges of drug toxicity, poor bioavailability and non-specificity for a number of drugs. Much progress has been reported for nano drug delivery ... -
In vivo/in vitro pharmacokinetic and pharmacodynamic study of spray-dried poly-(dl-lactic-co-glycolic) acid nanoparticles encapsulating rifampicin and isoniazid
(Elsevier, 2013)Poly-(dl-lactic-co-glycolic) acid (PLGA) nanoparticles were prepared by a double emulsion solvent evaporation spray-drying technique and coated with polyethylene glycol (PEG 1% v/v). The PLGA nanoparticles had a small ... -
Poly (D,L-lactide-co-glycolide) nanoparticles: uptake by epithelial cells and cytotoxicity
(Budapest University of Technology, 2014)Nanoparticles as drug delivery systems offer benefits such as protection of the encapsulated drug against degradation, site-specific targeting and prolonged blood circulation times. The aim of this study was to investigate ...