Browsing Faculty of Health Sciences by Author "Terre'blanche, Gisella"
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Inhibition of monoamine oxidase B by N-methyl-2-phenylmaleimides
Manley-King, Clarina I.; Terre'blanche, Gisella; Bergh, Jacobus J.; Petzer, Jacobus P.; Castagnoli, Neal (Elsevier, 2009)Based on a recent report that 1-methyl-3-phenylpyrrolyl analogues are moderately potent reversible inhibitors of the enzyme monoamine oxidase B (MAO-B), a series of structurally related N-methyl-2-phenylmaleimidyl analogues ... -
Interactions of 1-methyl-3-phenylpyrrolidine and 3-methyl-1-phenyl-3-azabicyclo[3.1.0]hexane with monoamine oxidase B
Pretorius, Anél; Ogunrombi, Modupe O.; Fourie, Hendrik; Terre'blanche, Gisella; Bergh, Jacobus J.; Petzer, Jacobus P. (Elsevier, 2010)The parkinsonian inducing agent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its corresponding five-membered ring analogue 1-methyl-3-phenyl-3-pyrroline are cyclic tertiary allylamines and good substrates of ...