Browsing Faculty of Health Sciences@PUK by Subject "caffeine"

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8-Aryl- and alkyloxycaffeine analogues as inhibitors of monoamine oxidase

Bergh, Jacobus Johannes; Petzer, Jacobus Petrus; Strydom, Belinda (Elsevier, 2011)

Recently it was reported that a series of 8-benzyloxycaffeine analogues are potent reversible inhibitors of human monoamine oxidase (MAO) A and B. In an attempt to discover additional C8 oxy substituents of caffeine that ...
Thio- and aminocaffeine analogues as inhibitors of human monoamine oxidase

Bergh, Jacobus Johannes; Booysen, Hermanus Perold; Moraal, Christina Maria; Petzer, Jacobus Petrus; Petzer, Anél; Terre'Blanche, Gisella (Elsevier, 2011)

In a recent study it was shown that 8-benzyloxycaffeine analogues act as potent reversible inhibitors of human monoamine oxidase (MAO) A and B. Although the benzyloxy side chain appears to be particularly favorable for ...