Browsing Faculty of Health Sciences@PUK by Subject "isatin"

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Inhibition of monoamine oxidase by selected C5- and C6-substituted isatin analogues

Bergh, Jacobus Johannes; Petzer, Jacobus Petrus; Manley-King, Clarina Ilara (Elsevier, 2011)

Previous studies have shown that (E)-5-styrylisatin and (E)-6-styrylisatin are reversible inhibitors of human monoamine oxidase (MAO) A and B. Both homologues are reported to exhibit selective binding to the MAO-B isoform ...