Search
Now showing items 1-5 of 5
Development of an LC-MS/MS method for the quantification of goserelin from Pheroid® formulation
(Elsevier, 2019)
The oral route is for many reasons the most common route of
drug administration, however, due to gastrointestinal (GI) tract
enzymatic stability issues, peptide drugs are administered parenterally. Goserelin is an ...
Establishment and characterization of allograft and xenograft cancer rodent models
(Elsevier, 2019)
To evaluate the efficacy of newly synthesized therapies prior to
clinical trials, valid and true cancer models should be used [1]. For
modelling cancer in vivo, transplantation of rodent (allograft) and
human cancer ...
The effect of entrapment of a peptide in Pheroid® on pharmacokinetics and testosterone levels
(Elsevier, 2019)
Goserelin is a peptide drug that suppresses levels of testosterone
and oestradiol [1]. The current formulation is presented in a
sustained-release depot with several approved indications such as
treatment of endometriosis, ...
Co-administration of African potato and cisplatin for treating breast and prostate cancers using a Pheroid® delivery system
(Elsevier, 2019)
The cancer burden is increasing worldwide and is expected tobecome the most important barrier to increasing life expectancy 21stcentury. Low- and middle-income countries are expected to showthe biggest increase in incidence. ...
Evaluation of the oral delivery of a peptide with Pheroid® technology
(Elsevier, 2019)
Goserelin is a type of hormone therapy used in addition to standard
adjuvant therapy. Currently, goserelin is only available as a slow
releasing subcutaneous implant but this is an invasive and generally not well- tolerated ...