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    Synthesis and evaluation of 2-substituted 4(3H)-quinazolinone thioether derivatives as monoamine oxidase inhibitors 

    Qhobosheane, Malikotsi A.; Petzer, Anél; Petzer, Jacobus P.; Legoabe, Lesetja J. (Elsevier, 2018)
    In the present study, a series of fourteen 2-mercapto-4(3H)-quinazolinone derivatives was synthesised and evaluated as potential inhibitors of the human monoamine oxidase (MAO) enzymes. Quinazolinone is the oxidised form ...
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    Synthesis and in vitro evaluation of 2-heteroarylidene-1-tetralone derivatives as monoamine oxidase inhibitors 

    Amakali, Klaudia T.; Legoabe, Lesetja J.; Petzer, Anél; Petzer, Jacobus P. (Thieme, 2018)
    The present study investigates the human monoamine oxidase (MAO) inhibition properties of a series of twelve 2-heteroarylidene-1-tetralone derivatives. Also included are related cyclohexylmethylidene, cyclopentylmethylidene ...

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    AuthorLegoabe, Lesetja J. (2)
    Petzer, Anél (2)
    Petzer, Jacobus P. (2)Amakali, Klaudia T. (1)Qhobosheane, Malikotsi A. (1)SubjectInhibition (2)Monoamine oxidase (2)
    Parkinson’s disease (2)
    2-Benzylidene-1-tetralone (1)Alzheimer’s disease (1)Heteroarylidene-1-tetralone (1)MAO (1)Quinazolinone (1)Reversible (1)... View MoreDate Issued
    2018 (2)
    Has File(s)No (2)

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