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Ethnic disparity in defensive coping endothelial responses: the SABPA study
(Elsevier, 2015)
Objectives:
Defensive coping (DefS) in Blacks has been associated with greater cardiovascular risk than in their White counterparts. We examined associations between endothelial function mental stress responses and markers ...
Defensive coping and renovascular disease risk. Adrenal fatigue in a cohort of Africans and Caucasians: the SABPA study
(Elsevier, 2015)
Background: Defensive coping is an established cardiovascular risk factor in Africans. Additionally, chronic, excessive or inadequate hypothalamic pituitary adrenal axis (HPAA) stress responses could either increase or ...
Defensive coping facilitated a smaller cortisol-to-estradiol ratio and a higher hypertension risk: the SABPA study
(Taylor & Francis, 2018)
Objectives: Taxing psychosocial stress and defensive coping have been associated with hypoactivity in cortisol, a vasoconstrictive agent. Estradiol has vasodilatory properties with cardio- and neuroprotective effects. It ...
Longitudinal changes of cardiac troponin and inflammation reflect progressive myocyte stretch and likelihood for hypertension in a Black male cohort: the SABPA study
(Springer, 2019)
Inflammation was cross-sectionally associated with subclinical wall remodeling and hypertension. Whether longitudinal changes (∆) in inflammation, myocyte injury (troponin T), and stretch (N-terminal-pro-B-type natriuretic ...
The defense response and alcohol intake: a coronary artery disease risk: the SABPA study
(Taylor & Francis, 2016)
The behavioral defense coping response (DefS) as a measure of coping with emotional stress may increase alcohol intake (gamma glutamyl transferase (γGT)), the risk for coronary artery disease (CAD) and insulin sensitivity ...
Troponin T release is associated with silent myocardial ischaemia in black men: the SABPA study
(Sage, 2017)
Background
High sensitivity cardiac troponin T (hs-cTnT) is a validated marker of myocardial damage and may reflect the degree of silent myocardial ischaemia (SMI) and ventricular strain. Our aim was to compare hs-cTnT ...
Chronic depression symptoms desensitize renin activity to protect against volume-loading hypertension in Blacks: the SABPA study
(Elsevier, 2018)
Background
Low-renin levels in Blacks have been associated with volume-loading hypertension (HT). Depression symptoms, frequently co-occurring with vascular dysregulation, might reflect a disturbed renin-angiotensin-ald ...
Hypercoagulation and hyperkinetic blood pressure indicative of physiological loss-of-control despite behavioural control in Africans: the SABPA study
(Taylor & Francis, 2016)
Objectives: A dissociation between behavioural (in-control) and physiological parameters (indicating loss-of-control) is associated with cardiovascular risk in defensive coping (DefS) Africans. We evaluated relationships ...
Hyperpulsatile pressure, systemic inflammation and cardiac stress are associated with cardiac wall remodeling in an African male cohort: the SABPA study
(Nature, 2016)
Inflammation may contribute to an increase in cardiac wall stress through pathways related to cardiac remodeling. Cardiac remodeling is characterized by myocyte hypertrophy, myocyte death and modifications of the extracellular ...
Fibrosis and coronary perfusion: a cardiovascular disease risk in an African male cohort: the SABPA study
(Taylor & Francis, 2016)
Low-grade inflammation has been correlated with risk factors of cardiovascular diseases (CVD). Whether the pro-inflammatory and thrombotic ratio (fibrosis) may contribute to CVD is not known. We therefore aimed to assess ...