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Thiobarbituric acid-reactive substances relate to arterial stiffness and blood pressure in 6 to 8-year-old boys stratified by maternal risk
(Nature, 2018)
Early cardiovascular disease (CVD) onset can be inflicted by familial cardiovascular and lifestyle risk factors. We aimed to compare phenotypic characteristics and explore associations between oxidative stress and vascular ...
GC-MS quantification of urinary symmetric dimethylarginine (SDMA), a whole-body symmetric l-arginine methylation index
(Elsevier, 2018)
Circulating and excretory NG,N´G-dimethyl-l-arginine (symmetric dimethylarginine, SDMA) and NG,NG-dimethyl-l-arginine (asymmetric dimethylarginine, ADMA) are cardiovascular risk factors. Despite close chemical structures, ...
Left ventricular mass independently associates with masked hypertension in young healthy adults: the African-PREDICT study
(Wolters Kluwer, 2018)
Objective: Masked hypertension is reportedly common in young adults. However, it is unknown if these masked hypertensive individuals already present with organ damage. We determined whether a relationship exists between ...
Large artery stiffness is associated with salt intake in young healthy black but not white adults: the African-PREDICT study + Correction to article
(Springer, 2018)
Purpose
There is global consensus on the benefits of reducing excessive salt intake. Indeed, lower salt intake associates with reduced arterial stiffness, a well-established predictor of cardiovascular risk, in older ...
Marinobufagenin and left ventricular mass in young adults: the African-PREDICT study
(Sage, 2018)
Background
The endogenous steroidal inhibitor of sodium–potassium-dependent adenosine triphosphate and natriuretic hormone, marinobufagenin, plays a physiological role in ionic homeostasis. Animal models suggest that ...
May Measurement Month 2017: an analysis of blood pressure screening results worldwide
(Elsevier, 2018)
Background
Increased blood pressure is the biggest contributor to the global burden of disease and mortality. Data suggest that less than half of the population with hypertension is aware of it. May Measurement Month was ...
Results, meta-analysis and a first evaluation of UNOxR, the urinary nitrate-to-nitrite molar ratio, as a measure of nitrite reabsorption in experimental and clinical settings
(Springer, 2018)
We recently found that renal carbonic anhydrase (CA) is involved in the reabsorption of inorganic nitrite (NO2−), an abundant reservoir of nitric oxide (NO) in tissues and cells. Impaired NO synthesis in the endothelium ...