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Development of an LC-MS/MS method for the quantification of goserelin from Pheroid® formulation
(Elsevier, 2019)
The oral route is for many reasons the most common route of
drug administration, however, due to gastrointestinal (GI) tract
enzymatic stability issues, peptide drugs are administered parenterally. Goserelin is an ...
The effect of entrapment of a peptide in Pheroid® on pharmacokinetics and testosterone levels
(Elsevier, 2019)
Goserelin is a peptide drug that suppresses levels of testosterone
and oestradiol [1]. The current formulation is presented in a
sustained-release depot with several approved indications such as
treatment of endometriosis, ...
Evaluation of the oral delivery of a peptide with Pheroid® technology
(Elsevier, 2019)
Goserelin is a type of hormone therapy used in addition to standard
adjuvant therapy. Currently, goserelin is only available as a slow
releasing subcutaneous implant but this is an invasive and generally not well- tolerated ...