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Ethnic differences regarding arterial stiffness of 6‐8‐year-old black and white boys
(Wolters Kluwer, 2017)
Objectives: Vascular deterioration is suggested to occur earlier in black than white populations, thereby increasing their risk for developing hypertension. To establish whether this is the case, we compared different ...
8-Oxo-7,8-dihydro-2’-deoxyguanosine, reactive oxygen species and ambulatory blood pressure in African and Caucasian men: the SABPA study
(Taylor & Francis, 2014)
Various studies indicate a relationship between increased oxidative stress and hypertension, resulting in increased DNA damage and consequent excretion of 8-oxo-7,8-dihydro-2’-deoxyguanosine (8-oxodG). The aim of this study ...
Defensive coping and renovascular disease risk. Adrenal fatigue in a cohort of Africans and Caucasians: the SABPA study
(Elsevier, 2015)
Background: Defensive coping is an established cardiovascular risk factor in Africans. Additionally, chronic, excessive or inadequate hypothalamic pituitary adrenal axis (HPAA) stress responses could either increase or ...
Leptin and its relation to autonomic activity, endothelial cell activation and blood pressure in a young black and white population: the African-PREDICT study
(Thieme, 2018)
An increasing prevalence of obesity-related hypertension is observed in the youth and may have severe consequences for future cardiovascular disease development. Previous studies portrayed leptin as a potential factor ...
Depression symptoms facilitated fibrinolytic dysregulation and future coronary artery disease risk in a black male cohort: the sympathetic activity and ambulatory blood pressure in Africans study
(Wolters Kluwer, 2017)
Background: Hypercoagulation is associated with coronary artery disease (CAD). Whether depression symptoms dysregulate inflammatory and hemostatic markers in an African cohort is not known; therefore, we assessed the ...
Chronic depression symptoms and salivary NOx are associated with retinal vascular dysregulation: the SABPA study
(Elsevier, 2016)
Background
Depression has been associated with impaired nitric oxide (NO)-mediated vasodilation and vascular dysregulation (VD). Whether depression and NO levels will disturb retinal haemodynamics is not clear.
Objectives ...
QTc prolongation, increased NT-proBNP and pre-clinical myocardial wall remodeling in excessive alcohol consumers: the SABPA study
(Elsevier, 2018)
Alcohol contributes greatly to vascular and structural modifications. Due to differences in the metabolism and tolerance of alcohol between ethnic groups, the manner of these modifications may differ. We investigated the ...
The association of endothelin-1 with markers of oxidative stress in a biethnic South African cohort: the SABPA study
(Springer Nature, 2017)
Both endothelin-1 and oxidative stress have important roles in the development of cardiovascular diseases such as hypertension and atherosclerosis. Limited information is available on the interaction between oxidative ...
Defensive coping and subclinical vascular disease risk – associations with autonomic exhaustion in Africans and caucasians: the SABPA study
(Elsevier, 2012)
Objective
The defensive active coping response is a recognised cardiovascular risk factor in Africans, especially in men. It is uncertain whether autonomic dysfunction might be the underlying cause. We therefore investigated ...
Ethnicity-specific differences in L-arginine status in South African men
(Nature Publishing Group, 2012)
The aetiology for an increasing incidence of hypertensive cardiovascular disease amongst Africans in southern Africa is unclear. Hypertension may be induced by inadequate release of L-arginine-derived nitric oxide impairing ...