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Leptin and its relation to autonomic activity, endothelial cell activation and blood pressure in a young black and white population: the African-PREDICT study
(Thieme, 2018)
An increasing prevalence of obesity-related hypertension is observed in the youth and may have severe consequences for future cardiovascular disease development. Previous studies portrayed leptin as a potential factor ...
Large artery stiffness is associated with marinobufagenin in young adults: the African-PREDICT study
(Wolters Kluwer, 2018)
Objectives: The cardiotonic steroid, marinobufagenin (MBG), has been shown to play a physiological natriuretic role in response to salt intake. However, recent studies in clinical and animal models demonstrated possible ...
Physical activity volume in relation to risk of atrial fibrillation. A non-linear meta-regression analysis
(Sage, 2018)
Background
Light physical activity is known to reduce atrial fibrillation risk, whereas moderate to vigorous physical activity may result in an increased risk. However, the question of what volume of physical activity can ...
Development of the certificate course in the management of hypertension in Africa (CCMH-Africa): proceedings of the first Continental Faculty Meeting, Nairobi, Kenya, 25-26 Feb 2018
(Clinics Cardive, 2018)
Background: In response to the call by the World Health Organisation to reduce premature deaths from non-commu- nicable diseases by 25% by the year 2025 (25×25), the Pan-African Society of Cardiology (PASCAR), in partner- ...
Monitoring the South African population’s salt intake: spot urine v. 24 h urine
(Cambridge Univ Press, 2018)
Objective
The present study set out to determine whether morning spot urine samples can be used to monitor Na (and K) intake levels in South Africa, instead of the ‘gold standard’ 24 h urine sample.
Design
Participants ...
What are the financial implications of the 2017 AHA/ACC High Blood Pressure Guideline?
(Sage, 2018)
Since the publication of the 2017 High Blood Pressure Guideline from the American College of Cardiology (ACC) and the American Heart Association (AHA),1 commentaries have been published debating medical perspectives on the ...
Left ventricular mass independently associates with masked hypertension in young healthy adults: the African-PREDICT study
(Wolters Kluwer, 2018)
Objective: Masked hypertension is reportedly common in young adults. However, it is unknown if these masked hypertensive individuals already present with organ damage. We determined whether a relationship exists between ...
Large artery stiffness is associated with salt intake in young healthy black but not white adults: the African-PREDICT study + Correction to article
(Springer, 2018)
Purpose
There is global consensus on the benefits of reducing excessive salt intake. Indeed, lower salt intake associates with reduced arterial stiffness, a well-established predictor of cardiovascular risk, in older ...
Marinobufagenin and left ventricular mass in young adults: the African-PREDICT study
(Sage, 2018)
Background
The endogenous steroidal inhibitor of sodium–potassium-dependent adenosine triphosphate and natriuretic hormone, marinobufagenin, plays a physiological role in ionic homeostasis. Animal models suggest that ...
Bioavailable IGF-1 is beneficially associated with biomarkers of endothelial function in young healthy adults: the African-PREDICT study
(Elsevier, 2018)
Low circulating levels of insulin-like growth factor-1 (IGF-1) are associated with endothelial dysfunction, subsequently leading to the development of cardiovascular disease.
Objective
To better understand the early ...