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Leptin and its relation to autonomic activity, endothelial cell activation and blood pressure in a young black and white population: the African-PREDICT study
(Thieme, 2018)
An increasing prevalence of obesity-related hypertension is observed in the youth and may have severe consequences for future cardiovascular disease development. Previous studies portrayed leptin as a potential factor ...
The African prospective study on the early detection and identification of cardiovascular disease and hypertension (African-PREDICT): design, recruitment and initial examination
(Sage, 2019)
Background: Globally hypertension is stabilising, but in sub-Saharan Africa the incidence of hypertension remains on an
increase. Although this might be attributed to poor healthcare and ineffective antihypertensive ...
Leptin and the retinal microvasculature in young black and white adults: the African-PREDICT study
(Elsevier, 2020)
Background
Leptin is a vasoactive peptide that has been linked to diseases associated with macrovascular deterioration. What is still uncertain is its involvement in the microvasculature. Since microvascular changes are ...
Retinal vessel caliber and caliber responses in true normotensive black and white adults: the African-PREDICT study
(Elsevier, 2020)
Purpose
Globally, a detrimental shift in cardiovascular disease risk factors and a higher mortality level are reported in some black populations. The retinal microvasculature provides early insight into the pathogenesis ...
Retinal vasculature reactivity during flicker light provocation, cardiac stress and stroke risk in Africans: the SABPA study
(Springer, 2019)
Structural and functional similarities exist between the retinal, cerebral and, as previously suggested, the coronary microvasculature. Retinal microvascular structure and functionality (in response to flicker-light-indu ...
Retinal vessel caliber and its relationship with nocturnal blood pressure dipping status: the SABPA study
(Springer Nature, 2016)
Adverse changes in retinal microvasculature caliber are associated with incident hypertension, coronary heart disease and stroke. The absence of a nocturnal dipping in arterial pressure may induce changes throughout the ...
IGF-1 and NT-proBNP in a black and white population: the SABPA study
(Wiley, 2016)
Background
Black populations exhibit lower concentrations of the cardioprotective peptide, insulin-like growth factor-1 (IGF-1), and are more prone to develop hypertensive heart disease than whites. We therefore determined ...