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Selected furanochalcones as inhibitors of monoamine oxidase
(Elsevier, 2013)
The validity of the chalcone scaffold for the design of inhibitors of monoamine oxidase has previously
been illustrated. In a systematic attempt to investigate the effect of heterocyclic substitution on the
monoamine ...
Inhibition of monoamine oxidase by selected phenylalkylcaffeine analogues
(Wiley, 2014)
Objectives Caffeine represents a useful scaffold for the design of monoamine
oxidase (MAO) type B inhibitors. Specifically, substitution on the C8 position
yields structures which are high-potency MAO-B inhibitors. To ...
Inhibition of monoamine oxidase by 8-phenoxymethylcaffeine derivatives
(Elsevier, 2012)
A recent study has reported that a series of 8-benzyloxycaffeines are potent and reversible inhibitors of both human monoamine oxidase (MAO) isoforms, MAO-A and -B. In an attempt to discover additional caffeine derivatives ...