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Attenuated IGF-1 predicts all-cause and cardiovascular mortality in a Black population: a five-year prospective study
(Sage Publications Ltd, 2016)
Background: Inconsistent findings are reported on whether insulin-like growth factor-1 (IGF-1) is protective or harmful in predicting hypertension, carotid wall thickness and mortality. We determined the five-year ...
Nitric oxide synthesis capacity, ambulatory blood pressure and end organ damage in a black and white population: the SABPA study
Nitric oxide (NO) synthesis capacity is determined by the availability of substrate(s) such as l-arginine and the influence of nitric oxide synthase (NOS) inhibitors, asymmetric dimethylarginine (ADMA) and symmetric ...
Using MutPred derived mtDNA load scores to evaluate mtDNA variation in hypertension and diabetes in a two-population cohort: the SABPA study
Mitochondrial DNA (mtDNA) variation has been implicated in many common complex diseases, but inconsistent and contradicting results are common. Here we introduce a novel mutational load hypothesis, which also considers the ...