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The interactions of caffeine with monoamine oxidase
(Elsevier, 2013)
Aims: Caffeine has been used as a scaffold for the design of inhibitors of monoamine oxidase (MAO) A and B.
Substitution at the C8 position with a variety of moieties yields structures with high MAO inhibition ...
Evaluation of natural and synthetic 1,4-naphthoquinones as inhibitors of monoamine oxidase
(Wiley, 2016)
Previous reports have documented that 1,4-naphtho-
quinones act as inhibitors of the monoamine oxidase
(MAO) enzymes. In particular, fractionation of the
extracts of cured tobacco leafs has led to the charac-
terization ...
The synthesis and evaluation of C7-substituted α-tetralone derivatives as inhibitors of monoamine oxidase
(Wiley, 2015)
Based on a previous report that α-tetralone (3,4-dihydro-2H-naphthalen-1-one) is a promising scaffold for the design of highly potent inhibitors of the enzyme, monoamine oxidase, the present study investigates the monoamine ...
The inhibition of monoamine oxidase by esomeprazole
(Thieme, 2013)
Virtual screening of a library of drugs has suggested that esomeprazole, the S-enantiomer of omeprazole, may possess binding affinities for the active sites of the monoamine oxidase (MAO) A and B enzymes. Based on this ...