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Whey protein/polysaccharide-stabilized oil powders for topical application: release and transdermal delivery of salicylic acid from oil powders compared to redispersed powders
(Springer, 2015)
Oil-in-water (o/w) emulsions are commonly converted into solid-like powders in order to
improve their physical and chemical stabilities. The aim of this study was to investigate whether whey
protein/polysaccharide-stabilized ...
In vitro permeation of metals through human skin: a review and recommendations
(American Chemical Society, 2015)
During the last few decades, the interest in skin permeation of, specifically, metals has increased with the in vitro method utilizing diffusion cells as the prominent method of investigating permeability. This review ...
Cutaneous tuberculosis overview and current treatment regimens
(Elsevier, 2015)
Tuberculosis is one of the oldest diseases known to humankind and it is currently a worldwide threat
with 8e9 million new active disease being reported every year. Among patients with co-infection of the
human immunodeficiency ...
Breaching the skin barrier through temperature modulations
(Elsevier, 2015)
The impermeability of the stratum corneum often hinders the transport of molecules across the skin. Temperature modulations in the skin and the application of local heat both have the potential of circumventing this problem ...
Penetration enhancing effects of selected natural oils utilized in topical dosage forms
(Taylor & Francis, 2015)
Context: Various natural products, including oils, have been utilized as penetration enhancers due to their “safety profiles”. These oils contain fatty acids promoting skin permeability through lipid fluidization within ...
Optimised transdermal delivery of pravastatin
(Elsevier, 2015)
Wiechers’ programme “Formulating for Efficacy” initiated a new strategy to optimise the oil phase of topical formulations in order to achieve optimal transdermal drug delivery. This new approach uses the “Delivery Gap ...
Skin permeation enhancement effects of the gel and whole 1 leaf materials of A. vera, A. marlothii and A. ferox
(Wiley, 2015)
Objectives: The aim of this study was to investigate the in vitro permeation enhancement effects of the gel and whole leaf materials of Aloe vera, Aloe marlothii and Aloe ferox using ketoprofen as a marker compound. Methods: ...
Stability, clinical efficacy and antioxidant properties of honeybush extracts in semi-solid formulations.
(Medknow Publications, 2015)
Background: Honeybush extracts (Cyclopia spp.) can be incorporated into skin care products to treat conditions such as skin dryness and can function as an anti-oxidant. Objective: To formulate Honeybush formulations and ...
In vitro anti-cancer effects of artemisone nano-vesicular formulations on melanoma cells
(Elsevier, 2015)
Artemisone is a 10-amino-artemisinin derivative that is markedly superior in vitro and in vivo to current artemisinins against malaria and also possesses antitumor activity. In seeking to capitalise on the last property, ...
Topical delivery of 5-fluorouracil from Pheroid™ formulations and the in vitro efficacy against human melanoma
(Springer, 2015)
Drug delivery vehicles can influence the topical delivery and the efficacy of an active pharmaceutical ingredient (API). In this study the influence of Pheroid™ technology, which is a unique colloidal drug delivery system, ...