Now showing items 151-153 of 153
Quantitative hippocampal structural changes following elctroconvulsive seizure treatment in a rat model of depression
Objective: The pathophysiology of depression and the effects of antidepressant treatment are hypothesized to be related to hippocampal structural changes. This study aims to investigate the effect of electroconvulsive ...
Selectively bred rodents as models of depression and anxiety
Stress related diseases such as depression and anxiety have a high degree of co morbidity, and represent one of the greatest therapeutic challenges for the twenty-first century. The present chapter will summarize existing ...
Effects of protein binding on the biodistribution of PEGylated PLGA nanoparticles post oral administration
The surface of nanoparticles is often functionalised with polymeric surfactants, in order to increase systemic circulation time. This has been investigated mainly for intravenously administered nanoparticles. This study ...