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The adenosine A2A antagonistic properties of selected C8-substituted xanthines
(Elsevier, 2013)
The adenosine A2A receptor is considered to be an important target for the development of new therapies
for Parkinson’s disease. Several antagonists of the A2A receptor have entered clinical trials for this purpose
and ...
Testosterone and acute stress are associated with fibrinogen and Von Willebrand factor in African men: the SABPA study
(Elsevier, 2013)
Background: Low testosterone, acute and chronic stress and hypercoagulation are all associated with hypertension
and hypertension-related diseases. The interaction between these factors and future risk for coronary ...
The link between vascular deterioration and branched chain amino acids in a population with high glycated haemoglobin: the SABPA study
(Springer Link, 2013)
Globally the prevalence of non-communicable diseases, such as hypertension and type 2 diabetes, are escalating. Metabolomic studies indicated that circulating branched chain amino acids (BCAAs) are associated with insulin ...
Towards a theory-based positive youth development programme
(Taylor & Francis, 2013)
The aim of this study was to develop and describe an intervention programme for young adolescents, guided by the Positive Youth Development Intervention (PYDI) model, which provides a perspective on the facilitation of ...
Changes in selected physical, motor performance and anthropometric components of university-level rugby players after one microcycle of a combined rugby conditioning and plyometric training program
(Lippincott, Williams & Wilkins, 2013)
Pienaar, C and Coetzee, B. Changes in selected physical, motor performance and anthropometric components of university-level rugby players after one microcycle of a combined rugby conditioning and plyometric training ...
The interactions of caffeine with monoamine oxidase
(Elsevier, 2013)
Aims: Caffeine has been used as a scaffold for the design of inhibitors of monoamine oxidase (MAO) A and B.
Substitution at the C8 position with a variety of moieties yields structures with high MAO inhibition ...
Traversing the skin barrier with nano-emulsions
(Bentham Science, 2016)
In recent years, colloidal delivery systems based on nano-emulsion are gaining popularity; being used for encapsulation and delivery of many drugs. Nano-emulsions are thermokinetically stable dispersion systems, which ...
Antimalarial activity of 10-alkyl/aryl esters and – aminoethylethers of artemisinin
(Elsevier, 2013)
A series of n-alkyl/aryl esters were synthesized and their in vitro antiplasmodial activity was measured
alongside that of previously synthesized aminoethylethers of artemisinin ozonides against various strains
of ...
Dermal exposure and changes in skin barrier function of base metal refinery workers co-exposed to cobalt and nickel
(The South African Society of Occupational Medicin, 2013)
Refi nery workers are exposed to many metals, including cobalt and nickel, both of which are skin sensitisers,
causing allergic contact dermatitis. Dermal exposure, and changes in skin barrier function [skin hydration,
...
Biodistribution and dosimetry of 195mPt-cisplatin in normal volunteers
(Schattauer, 2013)
195mPt-cisplatin is regarded as a promising
imaging agent for optimizing dosage in patients
receiving cisplatin chemotherapy. We
investigated the whole-body distribution and
radiation dosimetry of 195mPt-cisplatin in ...