Search
Now showing items 21-30 of 36
Left ventricular mass independently associates with masked hypertension in young healthy adults: the African-PREDICT study
(Wolters Kluwer, 2018)
Objective: Masked hypertension is reportedly common in young adults. However, it is unknown if these masked hypertensive individuals already present with organ damage. We determined whether a relationship exists between ...
Exploring the link between serum peroxides and angiogenesis in a bi-ethnic population from South Africa: the SAfrEIC study
(Elsevier, 2013)
Background:
Reactive oxygen species (ROS) play a fundamental role in angiogenesis, and in turn, angiogenic growth factors also affect ROS. Angiogenesis and ROS are intricately involved in vascular deterioration. Since ...
Leukocyte telomere length and hemostatic factors in a South African cohort: the SABPA study
(Wiley, 2014)
Background
Incident atherothrombotic disease is predicted by leukocyte telomere length, a marker of biological age, and hemostatic factor levels, indicating a hypercoagulable state. We hypothesized that shorter telomeres ...
Nitric oxide synthesis capacity, ambulatory blood pressure and end organ damage in a black and white population: the SABPA study
(Springer, 2016)
Nitric oxide (NO) synthesis capacity is determined by the availability of substrate(s) such as l-arginine and the influence of nitric oxide synthase (NOS) inhibitors, asymmetric dimethylarginine (ADMA) and symmetric ...
Retinal vessel caliber and its relationship with nocturnal blood pressure dipping status: the SABPA study
(Springer Nature, 2016)
Adverse changes in retinal microvasculature caliber are associated with incident hypertension, coronary heart disease and stroke. The absence of a nocturnal dipping in arterial pressure may induce changes throughout the ...
Leptin relates to prolonged cardiovascular recovery after acute stress in Africans: the SABPA study
(Elsevier, 2016)
Background and aims
Heightened cardiovascular reactivity and delayed recovery to stress are associated with an increased risk of cardiovascular disease. Africans, who are more prone to develop hypertension, show greater ...
Pulse pressure amplification and its relationship with age in young, apparently healthy black and white adults: the African-PREDICT study
(Elsevier, 2017)
Background
Pulse pressure amplification (PPA), i.e. the amplification from central arteries to the periphery, is inversely related to arterial stiffness, organ damage and mortality. It is known that arterial stiffness is ...
The defense response and alcohol intake: a coronary artery disease risk: the SABPA study
(Taylor & Francis, 2016)
The behavioral defense coping response (DefS) as a measure of coping with emotional stress may increase alcohol intake (gamma glutamyl transferase (γGT)), the risk for coronary artery disease (CAD) and insulin sensitivity ...
Antioxidant enzyme activity is associated with blood pressure and carotid intima media thickness in black men and women: the SABPA study
(Elsevier, 2016)
In the urbanized black population of South Africa, oxidative stress may play a crucial role in the development of hypertension. Since oxidative stress may result from impaired antioxidant capacity we aimed to investigate ...
IGF-1 and NT-proBNP in a black and white population: the SABPA study
(Wiley, 2016)
Background
Black populations exhibit lower concentrations of the cardioprotective peptide, insulin-like growth factor-1 (IGF-1), and are more prone to develop hypertensive heart disease than whites. We therefore determined ...