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A preclinical study of casein glycomacropeptide as a dietary intervention for acute mania
(Oxford Univ Press, 2018)
Background
Casein glycomacropeptide is a peptide that lacks phenylalanine, tyrosine, and tryptophan. This profile may enable it to deplete phenylalanine, tyrosine, and tryptophan, and subsequently the synthesis of dopamine ...
The role of triage to reduce waiting times in primary health care facilities in the North West province of South Africa
(AOSIS, 2018)
Background: Worldwide, patients visiting health care facilities in the public health care sector have to wait for attention from health care professionals. In South Africa, the Cape Triage Score system was implemented ...
Vitamin A supplementation among children aged 6-59 months in 23 sub-Saharan African countries
(Oxford Univ Press, 2018)
Background:
Vitamin A deficiency is a major contributor to under-five mortality. Improving vitamin A status of children through supplementation increases their resistance to disease and reduces childhood mortality.
...
NT-proBNP and metabolic risk factors in two ethnic groups: the SABPA cohort study
(Oxford Univ Press, 2018)
Background: Natriuretic peptides are vasoactive peptides with several metabolic
actions.
Purpose: We aimed to explore associations of N-terminal pro-brain natriuretic
peptide (NT-proBNP) with metabolic traits in a mixed ...
A review of the pharmacological properties of 3,4-dihydro-2(1h)- quinolinones
(Bentham Science, 2018)
The 3,4-dihydro-2(1H)-quinolinone moiety is present in a number of pharmacologically active compounds. These include FDA approved drugs such as cilostazol, carteolol and aripiprazole as well as numerous experimental ...
Pilot of a pharmacoepidemiology capacity building electronic survey for the Latin American and African regions
(Wiley, 2018)
Background: The ISPE Global Development Committee in collaboration with the Educational Committee and ISPE Board of Directors aims to build‐up pharmacoepidemiology (PE) research capacity in the Latin America (LatAm) and ...
Challenges and issues in drug utilization research identified from the Latin American and African regions
(Wiley, 2018)
Background: Despite advancements in drug utilization research (DUR),
these have not been universal. Some regions such as the Latin America
(LatAm) and African regions are facing challenges that are impeding
the development ...
Increasing access to drug utilization data globally: developing an action plan
(Wiley, 2018)
Background: Drug utilization (DU) research intends to support health authorities in the development of evidence‐informed pharmaceutical policy and practice guidelines, with the interest of the patients and communities in ...
Prevalence of potentially serious drug-drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol
(Wiley, 2018)
Objectives
To determine the prevalence of potentially serious drug–drug interactions (DDIs) and their relationship with gender and age, among elderly in South Africa.
Methods
A cross‐sectional study was conducted using ...
Preliminary evaluation of artemisinin-cholesterol conjugates as potential drugs for the treatment of intractable forms of malaria and tuberculosis
(Wiley, 2018)
To evaluate the feasibility of developing drugs that may be active against both malaria and tuberculosis (TB) by using in part putative cholesterol transporters in the causative pathogens and through enhancement of passive ...