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    2-Benzylidene-1-indanone derivatives as inhibitors of monoamine oxidase 

    Nel, Magdalena S.; Petzer, Anél; Petzer, Jacobus P.; Legoabe, Lesetja J. (Elsevier, 2016)
    In the present study, a series of twenty-two 2-benzylidene-1-indanone derivatives were synthesised and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) A and B. The 2-benzylidene-1-indanone derivatives ...
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    Inhibition of monoamine oxidase by benzoxathiolone analogues 

    Mostert, Samantha; Petzer, Anél; Petzer, Jacobus P. (Elsevier, 2016)
    Inhibitors of the monoamine oxidase (MAO) enzymes are considered useful therapeutic agents, and are used in the clinic for the treatment of depressive illness and Parkinson’s disease. In addition, MAO inhibitors are also ...
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    Evaluation of natural and synthetic 1,4-naphthoquinones as inhibitors of monoamine oxidase 

    Mostert, Samantha; Petzer, Anél; Petzer, Jacobus P. (Wiley, 2016)
    Previous reports have documented that 1,4-naphtho- quinones act as inhibitors of the monoamine oxidase (MAO) enzymes. In particular, fractionation of the extracts of cured tobacco leafs has led to the charac- terization ...
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    Leflunomide, a reversible monoamine oxidase inhibitor 

    Petzer, Jacobus P.; Petzer, Anél (Bentham Science, 2016)
    A screening study aimed at identifying inhibitors of the enzyme, monoamine oxidase (MAO), among clinically used drugs have indicated that the antirheumatic drug, leflunomide, is an inhibitor of both MAO isoforms. Leflunomide ...

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    AuthorPetzer, Anél (4)Petzer, Jacobus P. (4)Mostert, Samantha (2)Legoabe, Lesetja J. (1)Nel, Magdalena S. (1)Subject
    Inhibition (4)
    Monoamine oxidase (4)
    Reversible (4)
    MAO (3)1,4-Naphthoquinone (1)2-Benzylidene-1-indanone (1)Benzoxathiolone (1)Competitive (1)Dialysis (1)Isoxazole (1)... View MoreDate Issued
    2016 (4)
    Has File(s)
    No (4)

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