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Ozone modulates the effects of imipramine on immobility in the forced swim test, and nonspecific parameters of hippocampal oxidative stress in the rat
(Springer, 2010)
Depression has been associated with oxidative stress. There is increased awareness of the role of environmental toxins in the development of mood disorders. Ozone, a pro-oxidant and environmental pollutant, has been noted ...
Increased stress-evoked nitric oxide signaling in the Flinders sensitive line (FSL) rat: a genetic animal model of depression
(Oxford Univ Press, 2010)
Stress engenders the precipitation and progression of affective disorders, while stress-related release of excitatory mediators is implicated in the degenerative pathology observed especially in the hippocampus of patients ...