Now showing items 1-4 of 4
2-Benzylidene-1-indanone derivatives as inhibitors of monoamine oxidase
In the present study, a series of twenty-two 2-benzylidene-1-indanone derivatives were synthesised and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) A and B. The 2-benzylidene-1-indanone derivatives ...
Inhibition of monoamine oxidase by benzoxathiolone analogues
Inhibitors of the monoamine oxidase (MAO) enzymes are considered useful therapeutic agents, and are used in the clinic for the treatment of depressive illness and Parkinson’s disease. In addition, MAO inhibitors are also ...
Evaluation of natural and synthetic 1,4-naphthoquinones as inhibitors of monoamine oxidase
Previous reports have documented that 1,4-naphtho- quinones act as inhibitors of the monoamine oxidase (MAO) enzymes. In particular, fractionation of the extracts of cured tobacco leafs has led to the charac- terization ...
Leflunomide, a reversible monoamine oxidase inhibitor
(Bentham Science, 2016)
A screening study aimed at identifying inhibitors of the enzyme, monoamine oxidase (MAO), among clinically used drugs have indicated that the antirheumatic drug, leflunomide, is an inhibitor of both MAO isoforms. Leflunomide ...