Browsing Faculty of Natural and Agricultural Sciences by Subject "Cardiovascular disease"
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The aetiology of cardiovascular disease: a role for mitochondrial DNA?
(Clinics Cardive Publishing, 2018)Cardiovascular disease (CVD) is a world-wide cause of mortality in humans and its incidence is on the rise in Africa. In this review, we discuss the putative role of mitochondrial dysfunction in the aetiology of CVD and ... -
A comparison of the cardiometabolic profile of black South Africans with suspected non-alcoholic fatty liver disease (NAFLD) and excessive alcohol use
(Elsevier, 2015)Excessive alcohol use and non–alcoholic fatty liver disease (NAFLD) are putative cardiovascular disease risk factors. In order to ease the identification of these conditions on primary health care level, we aimed to determine ... -
Leukocyte telomere length and hemostatic factors in a South African cohort: the SABPA study
(Wiley, 2014)Background Incident atherothrombotic disease is predicted by leukocyte telomere length, a marker of biological age, and hemostatic factor levels, indicating a hypercoagulable state. We hypothesized that shorter telomeres ... -
Self-reported alcohol intake is a better estimate of 5-year change in blood pressure than biochemical markers in low resource settings: the PURE study
(Wolters Kluwer, 2014)Background: Despite criticism of self-reported alcohol intake, it is a valuable tool to screen for alcohol abuse as a risk factor for cardiovascular disease. We aimed to compare various self-reported estimates of alcohol ...