Now showing items 1-3 of 3

    • Cell-free DNA: preanalytical variables 

      Bronkhorst, Abel Jacobus; Aucamp, Janine; Pretorius, Piet J. (Elsevier, 2015)
      Since the discovery of cell-free DNA (cfDNA) in human blood, most studies have focused on diagnostic and prognostic uses of these markers for solid tumors. Except for some prenatal tests and BEAMing, cfDNA analysis has not ...
    • Continuous adaptation through genetic communication – a putative role for cell-free DNA 

      Peters, Dimetrie Leslie; Pretorius, Petrus Jacobus (Informa healthcare, 2012)
      Introduction: The virtosome fraction of cell-free DNA, being newly synthesised, capable of horizontal gene transfer (HGT) and subsequent genomic incorporation and expression, may play crucial roles in the biological functions ...
    • Origin, translocation and destination of extracellular occurring DNA: a new paradigm in genetic behaviour 

      Peters, Dimetrie Leslie; Pretorius, Petrus Jacobus (Piet) (Elsevier Science, 2011)
      The diagnostic value of extracellular occurring DNA (eoDNA) is limited by our lack of understanding its biological function. eoDNA exists in a number of forms, namely vesicle bound DNA (apoptotic bodies, micro particles, ...