Browsing Faculty of Natural and Agricultural Sciences by Author "Hamman, Josias H."
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Combining chemical permeation enhancers for synergistic effects
Du Toit, Trizel; Malan, Maides M.; Lemmer, Hendrik J.R.; Gouws, Chrisna; Aucamp, Marique E.; Breytenbach, Wilma J.; Hamman, Josias H. (Springer, 2016)Currently, macromolecular drugs such as proteins are mainly administered by means of injections due to their low intestinal epithelial permeability and poor stability in the gastrointestinal tract. This study ... -
The SeDeM expert diagram system: its performance and predictability in direct compressible formulations containing novel excipients and different types of active ingredients
Scholtz, Jacques C.; Steenekamp, Jan H.; Hamman, Josias H.; Tiedt, Louwrens R. (Elsevier, 2017)The SeDeM Expert Diagram System is a galenic pre-formulation system, which evaluates the suitability of excipients and active pharmaceutical ingredients (API's) for direct compression into tablets as well as predicting ...