Browsing Faculty of Natural and Agricultural Sciences by Author "Lindeque, Jeremie Zander"
Now showing items 1-2 of 2
-
Metallothionein 1 overexpression does not protect against mitochondrial disease pathology in Ndufs4 knockout mice
Miller, Hayley Christy; Louw, Roan; Mereis, Michelle; Venter, Gerda; Boshoff, John-Drew; Mienie, Liesel; Van Reenen, Mari; Venter, Marianne; Lindeque, Jeremie Zander; Van der Westhuizen, Francois Hendrikus (Springer, 2021)Mitochondrial diseases (MD), such as Leigh syndrome (LS), present with severe neurological and muscular phenotypes in patients, but have no known cure and limited treatment options. Based on their neuroprotective effects ... -
Systemic and organ specific metabolic variation in metallothionein knockout mice challenged with swimming exercise
Lindeque, Jeremie Zander; Louw, Roan; Van der Westhuizen, Francois Hendrikus; Hidalgo, Juan (Springer, 2013)Metallothioneins (MTs) are ubiquitous, multifunctional proteins with key roles in metal homeostasis and redox regulation. Their involvement in cellular energy metabolism is evident from the observation that metallothi ...