Browsing Faculty of Natural and Agricultural Sciences by Subject "Parkinson's disease"
Now showing items 1-3 of 3
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C2-substituted quinazolinone derivatives exhibit A1 and/or A2A adenosine receptor affinities in the low micromolar range
(Elsevier, 2020)Antagonists of the adenosine receptors (A1 and A2A subtypes) are widely researched as potential drug candidates for their role in Parkinson’s disease-related cognitive deficits (A1 subtype), motor dysfunction (A2A subtype) ... -
Deep-brain stimulation associates with improved microvascular integrity in the subthalamic nucleus in Parkinson's disease
(Elsevier, 2015)Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has become an accepted treatment for motor symptoms in a subset of Parkinson's disease (PD) patients. The mechanisms why DBS is effective are incompletely ... -
The unresolved role of mitochondrial DNA in Parkinson's disease: an overview of published studies, their limitations, and future prospects
(Elsevier, 2019)Parkinson's disease (PD), a progressive neurodegenerative disorder, has long been associated with mitochondrial dysfunction in both sporadic and familial forms of the disease. Mitochondria are crucial for maintaining ...