Browsing Faculty of Natural Sciences@PUK by Subject "amplification and 454® pyrosequencing"

Now showing items 1-1 of 1

Whole genome analysis of multiple rotavirus strains from a single stool specimen using sequence-independent amplification and 454® pyrosequencing reveals evidence of intergenotype genome segment recombination

Jere, Khuzwayo; Mlera, Luwanika; Van Dijk, Alberdina Aike; Page, Nicola A.; O'Neill, Hester Gertruida (Elsevier, 2011)

Infection of a single host cell with two or more different rotavirus strains creates conditions favourable for evolutionary mechanisms like reassortment and recombination that can generate novel strains. Despite numerous ...