Browsing ETD@PUK by Subject "Depressive-like behaviour"
Now showing items 1-4 of 4
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Early-life exposure to fluoxetine and/or exercise on bio-behavioural markers of depression in early adulthood in stress sensitive rats
(North-West University (South Africa) , Potchefstroom Campus, 2015)Juvenile depression is a major concern worldwide, with only the selective serotonin reuptake inhibitors (SSRIs) fluoxetine and escitalopram approved for treatment. The effects of early-life exposure to SSRIs on neurodevelopment ... -
Effects of early-life administration of methamphetamine on the depressive-like behaviour later in life in stress-sensitive and control rats
(2013)Methamphetamine (MA) is a well-known, easily accessible and powerful psychostimulant, and its abuse has become a global problem. MA abuse affects millions of people worldwide and places an enormous burden on public healthcare ... -
The long-term effects of fluoxetine on stress-related behaviour and acute monoaminergic stress response in stress sensitive rats
(2014)Fluoxetine and escitalopram are the only antidepressants approved by the Food and Drug Administration of the United States of America (FDA) for treatment of major depression in children and adolescents. Both drugs are ... -
The long-term effects of methamphetamine on depressive-like behaviour and neuroplasticity in stress-sensitive rats
(2014)Methamphetamine (METH) abuse has become a fast growing drug problem that has developed into a global epidemic. In fact, METH is one of the most commonly abused substances with an estimated 35 million abusers worldwide and ...
