Browsing Electronic Theses and Dissertations (ETDs) by Subject "Cell-free DNA"
Now showing items 1-3 of 3
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Development and validation of a qPCR assay for the non-invasive determination of fetal sex in cattle and African Buffalo
(North-West University (South Africa)North-West University, 2020)The expansive possibilities and research progress of cell-free DNA (cfDNA) and cell-free foetal DNA (cffDNA) have engendered numerous articles published on a regular basis in recent years. However, this has mainly been ... -
Molecular and biological characterization of cell-free DNA using an in vitro cell culture model
(North-West University, Potchefstroom Campus, 2017)Over the past 40 years, numerous proof-of-principle studies have intermittently demonstrated the translational potential of cfDNA as a non-invasive biomarker for the diagnostication, prognostication and therapy monitoring ... -
Transmission of clinical risk factors through circulating DNA
(North-West University (South Africa), Potchefstroom Campus, 2017)Newly synthesised, actively released circulating DNA can translocate to neighbouring and remote parts of the body, enter cells and alter their biology. It has been implicated in the bystander effect, tumour development ...