Browsing Electronic Theses and Dissertations (ETDs) by Subject "Antagonist"
Now showing items 1-2 of 2
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Adenosine A1/A2A receptor antagonistic properties of selected 2-substituted benzoxazinone and quinazolinone derivatives
(North-West University (South Africa), Potchefstroom Campus, 2018)The A1 and A2A adenosine receptor antagonists are the subject of extensive research based on their aptitude for ameliorating Parkinson’s disease related cognitive deficits (A1 adenosine receptor subtype) and motor dysfunction ... -
Syntheses of sulfanylphthalimide and xanthine analogues and their evaluation as inhibitors of monoamine oxidase and as antagonists of adenosine receptors
(North-West University, 2013)Currently L-DOPA is the drug most commonly used for the treatment of Parkinson’s disease (PD). However, the long-term use of L-DOPA is associated with the development of motor fluctuations and dyskinesias. Treatment mainly ...