Browsing Health Sciences by Title
Now showing items 1259-1278 of 2060
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A model to facilitate the Integration of Indigenous Kowledge Systems in the management of HIV & AIDS within a Primary Health Care context in Limpopo Province, South Africa
(2015)Indigenous health practices have been in existence since the dawn of civilization, and the inception of western medical practices has created a divide between these health systems. This study focused on the development of ... -
Modelling primary health care workforce needs towards health professions education and employment investment planning in Ghana
(North-West University (South Africa), 2021)The health workforce is a critical part of developing responsive health systems that address routine population health needs and responding to health emergencies. However, defective planning has resulted in underinvestment ... -
The modulating effect of myo-inositol and other antidepressants on the mRNA levels and protein expression of selected subcellular enzymes
(North-West University, 2005)Myo-lnositol (mIns), a natural component of the human diet and essential precursor of several signalling pathways, including that of G protein-coupled receptors, has also been shown to be effective in the treatment of ... -
The modulating effect of myo-inositol and prototypical antidepressants on markers of cellular resilience in cultured human neuroblastoma cells
(North-West University, 2006)Although several antidepressants are available for the treatment of depression, certain limitations are common, including drug resistance and significant side effects. Recently, several studies indicated the possibility ... -
The modulating effect of sildenafil on cell viability and on the function of selected pharmacological receptors in cell cultures
(North-West University, 2004)Since sildenafil's (Viagra®), a phospodiesterase type 5 (PDE5) inhibitor, approval for the treatment of male erectile dysfunction (MED) in the United States early 1998, 274 adverse event reports were filed by the Food and ... -
The modulating effects of selected antidepressants and related drugs on markers of cellular resilience in cultured human neuroblastoma cells
(North-West University, 2008)The neurodegenerative hypothesis of depression postulates that major depression is associated with impaired neuroplasticity, particularly in the hippocampus and prefrontal cortex, and that effectiveness of antidepressants ... -
The modulatory effects of sildenafil and the cholinergic system on antidepressant action in a rat model of depression
(North-West University, 2006)Sildenafil, a selective phosphodiesterase type 5 (PDE5) inhibitor, is registered for the treatment of male erectile dysfunction (Viagra®) and pulmonary hypertension (Revatio®) in the United States. PDE5 is found in the ... -
Molecular and biological characterization of cell-free DNA using an in vitro cell culture model
(North-West University, Potchefstroom Campus, 2017)Over the past 40 years, numerous proof-of-principle studies have intermittently demonstrated the translational potential of cfDNA as a non-invasive biomarker for the diagnostication, prognostication and therapy monitoring ... -
Molecular and pharmacological studies into a mouse model (Peromyscus maniculatus bairdii) of obsessive compulsive disorder
(North-West University, 2007)There have been various attempts to develop animal models of obsessive compulsive disorder (OCD) in the hope that they may provide a means to better understand and treat this disorder. Given that the aetiology of OCD ... -
Monitoring and control of hazardous chemical substances in research and testing laboratories in the Faculty of Health Sciences of the North-West University
(North-West University, 2007)This study was launched because of alarming conditions in laboratories and lack of general occupational health and safety. Employees are exposed to a number of chemicals for extended periods of time, and these employees ... -
Monitoring the reduction of sodium content of selected food items using label information in South Africa
(North-West University (South Africa) , Potchefstroom Campus, 2015)Background Hypertension is a growing concern, not only in South Africa, but worldwide. Sodium (salt) intake has been proven to have a major effect on the development of cardiovascular diseases and hypertension. It will ... -
The monoamine oxidase B substrate properties of selected pyrrolinyl analogues
(North-West University, 2008)The parkinsonian inducing agent, 1-rnethyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), is a cyclic tertiary allylamine that is oxidized by monoamine oxidase B (MAO-B) at the ring a-carbon to yield the 1-rnethyl-4-pheny ... -
Monoamine oxidase inhibition by indanone and benzoquinone analogues
(North-West University (South Africa) , Potchefstroom Campus, 2015)Parkinson’s disease (PD) is a neurological disorder of which aging is the greatest risk factor. Over the next fifteen years, the number of persons affected by PD worldwide is expected to increase from 4.6 million to 9.3 ... -
Monoamine oxidase inhibition by novel quinolinones
(2014)Parkinson’s disease (PD) is an age-related neurodegenerative disorder. The degeneration of the neurons of the substantia nigra in the midbrain leads to the loss of dopamine from the striatum, which is responsible for the ... -
The monoamine oxidase inhibition properties of caffeine analogues containing saturated C–8 substituents
(North-West University, 2010)Parkinson’s disease (PD) is a progressive neurodegenerative disorder, characterized pathologically by a marked loss of dopaminergic nigrostriatal neurons and clinically by disabling movement disorders. PD can be treated ... -
Monoamine oxidase inhibition properties of quinolinone analogues
(North-West University (South Africa), Potchefstroom Campus, 2016)Parkinson's disease (PD) is an age-related neurodegenerative disorder characterised by selective loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) of the brain. This leads to the loss of dopamine ... -
Monoamine oxidase inhibitory activities of heterocyclic chalcones
(2013)Parkinson’s disease is the second most common age-related neurodegenerative disease after Alzheimer’s disease. The characteristic pathological feature of Parkinson’s disease is the loss of neurons in the substantia nigra ... -
Monocyte chemoattractant protein-1 and large artery structure and function in young individuals : the African-PREDICT study
(North-West University (South Africa) , Potchefstroom Campus, 2015)Motivation - In sub-Saharan Africa, the burden of cardiovascular diseases (CVD) is increasing at an alarming rate. This may be due to the rapid urbanisation of traditional black populations, leading to lifestyle changes ... -
Moral distress in South African professional nurses : instrument development
(2014)Nurses experience stress, fear and anger while they are trying to reconcile their ideals/ goals about health care with its inadequacies and abuses (Jameton, 1984:5), while at the same time trying to stay true to their ... -
Morfologiese onderskeiding tussen verskillende serotipes van Pseudomonas aeruginosa uit hospitaal infeksies
(North-West University (South-Africa), 1979)Met hierdie studie van flagella van verskillende H-serotipes van P. aeruginosa kon twee tipes flagellastrukture, (A en B) waargeneern word. Uit die resultate kan aangeneem word dat die flagellastruktuur van 'n spesifieke ...