Browsing Health Sciences by Title
Now showing items 24-43 of 2060
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Alcohol intake and cardiovascular function of black South Africans : a 5-year prospective study
(2015)Motivation - Alcohol consumption is one of the major risk factors of cardiovascular disease (CVD). Excessive alcohol drinking is the fifth leading cause of death worldwide and the prevalence of alcohol abuse continues to ... -
Aminopyrimidine derivatives as adenosine antagonists
(2013)Aims of this project - The aim of this study was to design and synthesise novel 2-aminopyrimidine derivatives as potential adenosine A1 and A2A receptor antagonists. Background and rationale - Parkinson’s disease is the ... -
Amorphism and polymorphism of azithromycin
(North-West University, 2012)Azithromycin, an azalide and member of the macrolide group, is a broad spectrum antimicrobial, representing one of the bestselling antimicrobials worldwide. It is derived from erythromycin and exhibits improved acidic ... -
An analysis of antidepressant noncompliance in the private health sector of South Africa
(2014)The main aim of the thesis was to measure antidepressant (AD) non-compliance, to determine which factors are closely associated with AD non-compliance and the consequences of prolonged AD non-compliance in the private ... -
An analysis of medication adherence among epileptic patients in the private health sector of South Africa
(North-West University (South Africa) , Potchefstroom Campus, 2015)Failure to respond to anti-epileptic (AED) treatment and achieving control over epilepsy has severe clinical consequences. The clinical consequences include an increase in the frequency of seizures and increased work and ... -
An analysis of the usage of antibiotics in the private health care sector : a managed health care approach
(North-West University, 2004)The most frequent intervention performed by physicians is the writing of a prescription. Modern medicine has been remarkably effective in managing diseases. Medicines play a fundamental role in the effectiveness, efficiency ... -
Anatomical alignment and muscle strength as predictors of overuse injuries in long-distance athletes
(North-West University (South-Africa), 2000)Background - Running is a popular choice of physical activity for many people because it is relatively inexpensive and not bound to a high-tech facility (Mann et al. , 1981 : 190). Associated with the increased ... -
Antagonism by selected classical irreversible competitive antagonists : an investigation into the proposed non-specific mechanisms involved
(North-West University, 2003)Many irreversible antagonists are known to bind irreversibly to pharmacological receptors. However, few studies suggest that these irreversible antagonists may also display irreversible non-specific antagonism by binding ... -
Antenatal care for HIV positive women
(North-West University, 2007)Approximately 29.1% of South African women of childbearing age tested HIV positive during their first antenatal visit in 2006 (DoH, 2007). This rate of HIV amongst the women of childbearing age reinforces the importance ... -
Anthropometric profile, selected physical parameters, technical skills and match demands of university-level female soccer players
(North-West University, 2018)Female soccer has increased in popularity in recent years. No research exist on the physical and match performance of female soccer players in South Africa, while limited information discussing these components on sub-elite ... -
Anthropometrical indicators of non-communicable diseases for a black South African population in transition
(North-West University, 2009)Non-communicable diseases (NCD) are also known as chronic diseases of lifestyle and cause the greatest burden of disease globally, whether measured as morbidity or mortality. Although there is consensus that obesity is a ... -
Antibiotic exposure as a risk factor for secondary Candida infections in a private hospital intensive care unit
(North-West University (South Africa), 2020)Candida is the most common fungal pathogen and the leading cause of invasive candidiasis in humans. The range of infections caused by Candida is vast, and the increased use of potent broad-spectrum antimicrobial agents ... -
Antibiotic usage in South Africa: a longitudinal analysis of medicine claims data
(2014)The main aim of the study was to determine the prescribing patterns of antibiotics with an emphasis on fluoroquinolones in the private health sector of South Africa. The empirical study followed a quantitative, descriptive, ... -
Antibiotic use and resistance patterns in the Namibian private health sector
(North-West University (South Africa) , Potchefstroom Campus, 2016)The general aim of this study was to understand antibiotic use in the private health sector of Namibia. Specifically, the study set out to ascertain the relationship, if any, between prescribing patterns, antibiotic use ... -
Anticancer activities of oxidant-redox drug combinations in lipid excipients
(North-West University, 2018)Genetic alterations in the redox status of cancer cells promotes a continuous and elevated production of reactive oxygen species (ROS), associated in the initiation and progression of tumours. The body's potent antioxidant ... -
Anticancer efficacy of selected South African phytomedicines in a three-dimensional colorectal cancer model
(North-West University (South-Africa), 2020)Millions of patients die from cancer each year, with colorectal cancer being one of the leading causes. Chemotherapeutic drugs are routinely used in cancer treatment, but unfortunately these treatments have severe side ... -
The antidepressant properties of selected methylene blue analogues
(2014)The shortcomings of current antidepressant agents prompts the design of novel multimodal antidepressants and the identification of new antidepressant targets, especially those located at sub-cellular level. Such ... -
Antidepressant usage by South African children and adolescents : a drug utilisation review
(2013)This study set out to review and analyse aspects of antidepressant prescribing in children and adolescents in a section of the private health care sector of South Africa. The research was conducted in two phases, namely a ... -
Antigenic properties of snake venom cardiotoxins
(North-West University (South-Africa), 1989)In this dissertation an innitial investigation was made to lo~ate antigenic determinants of cardiotoxin vll 1 from N.nivea with a future view of applying the knowledge obtained in the design of synthetic vaccines. The ... -
Antihistamines as neuroprotective agents
(North-West University, 2004)Biomolecules are continuously exposed to potentially harmful oxidative stress as a consequence of free radical formation. Increased free radical generation has been associated with aging as well as neurodegenerative ...