Browsing Health Sciences by Title
Now showing items 910-929 of 2060
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Formulation of 5–Fluorouracil for transdermal delivery
(North-West University, 2010)Non–melanoma skin cancer (NMSC) is the most common human malignancy and it is estimated that over 1.3 million cases are diagnosed each year in the United States (Neville et al., 2007:462). There are three main types of ... -
Formulation of a chitosan multi-unit dosage form for drug delivery to the colon
(North-West University, 2006)In some diseases it is preferable that the drugs used in their treatment are released in the colon. The colon is also suitable for systemic delivery of a variety of drugs. A variety of systems have been developed for the ... -
Formulation of a multiple-unit pellet solid oral delivery system for metformin and gliclazide
(North-West University, 2018)Non-compliance is one of the contributing factors leading to poor treatment response in patients with chronic conditions such as diabetes mellitus (DM), due to the complex regimens often used in the management of these ... -
Formulation of an emulgel for topical delivery of roxithromycin
(North-West University (South-Africa), 2020)The aim of this study was to establish whether liposomal or niosomal vesicle systems containing roxithromycin could be developed further into semi-solid formulations (emulgels) for topical delivery of the active pharmaceutical ... -
Formulation of ascorbyl phosphate in cosmeceutical products
(North-West University, 2012)People and especially women are forever searching for new and improved ways to alter the appearance of their skin. Skin can be prematurely aged by various environmental factors, including prolonged exposure to ultraviolet ... -
Formulation of cosmetic products for the treatment of acne containing tea tree oil and salicyclic acid
(North-West University, 2005)Acne is a skin disease that affects most adolescents and young adults. There are four abnormalities in acne namely, sebum production, inflammation, hyperkeratosis and the presence of Propionobacterium acnes. To treat acne ... -
The formulation of different dosage forms with the anthelmintics : Levamisole, Niclosamide and Oxyclozanide
(North-West University, 2003)Different formulations of dosage forms of niclosamide, levamisole HCI or levamisole HCI and oxyclozanide have been used on the local market for a very long time. Unfortunately, the spectrum of each of the drugs alone has ... -
The formulation of scale items for the best interest of the child
(North-West University (South-Africa), 2020)Although there is a high reported incidence of child sexual abuse cases in South Africa, which in itself is cause for concern, a great concern is what happens to children who have reported abuse to the authorities. To what ... -
Formulation, characterisation and in vivo efficacy of dapsone and proguanil in trimethylated chitosan microparticles
(2014)Malaria is an infectious disease caused by various forms of the Plasmodium parasite. It is responsible for thousands of deaths yearly with 90 % of those deaths being in sub-Saharan Africa, thus making it a disease of global ... -
Formulation, characterisation and topical application of oil powders from whey protein stabilised emulsions
(2014)The available literature indicates that to date, few research has been performed on oil powders for topical delivery. The aim of this project was to investigate the release characteristics of oil powder formulations, as ... -
Formulation, characterisation and topical delivery of salicylic acid containing whey–protein stabilised emulsions
(2014)Emulsions are widely used as topical formulations in the pharmaceutical and cosmetic industry. They are thermodynamically unstable and require emulsifiers to stabilize them physically. A literature survey has revealed that ... -
Formulation, characterization and cellular toxicity of lipid based drug delivery systems for mefloquin
(North-West University, 2011)Malaria affects millions of people annually especially in third world countries. Increase in resistance and limited research being conducted adds to the global burden of malaria. Mefloquine, known for unwanted adverse ... -
Formulation, in vitro release and transdermal diffusion of acyclovir and ketoconazole for skin conditions in HIV/AIDS patients
(North-West University, 2009)The aim of this in vitro study was to investigate the efficacy of the novel Pheroid™ technology system in a semi-solid dosage form, for the topical delivery of acyclovir (5% w/w), an anti-viral agent and ketoconazole (2% ... -
Formulation, in vitro release and transdermal diffusion of anti-inflammatory gel preparations containing diclofenac salts
(North-West University, 2010)Most individuals are influenced by pain at some stage in their lives. It can either be of acute or chronic nature. An acute pain condition initiates and is treated within a time span of 12 weeks. Chronic pain can, however, ... -
Formulation, in vitro release and transdermal diffusion of atropine by implementation of the delivery gap principle
(2014)The transdermal delivery route has become a popular alternative to more conventional routes, such as oral administration, but has not yet reached its full potential (Prausnitz & Langer, 2008:1261). Although the transdermal ... -
Formulation, in vitro release and transdermal diffusion of azelaic acid with topical niacinamide
(North-West University, 2010)Acne is a common skin disease that affects the follicular unit of the skin. Inflammatory- and noninflammatory forms of acne exist. The most affected areas on the body include the face, upper part of the chest and the back. ... -
Formulation, in vitro release and transdermal diffusion of diclofenac salts by implementation of the delivery gap principle
(2013)Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used in the treatment of inflammation and pain (Escribano et al., 2003:203). Diclofenac, a classical NSAID, is considerably more effective as an analgesic, antipyretic ... -
Formulation, in vitro release and transdermal diffusion of isoniazide and rifampicin for dermal tuberculosis
(North-West University, 2009)Extra pulmonary tuberculosis makes up 10% of all tuberculosis cases and cutaneous tuberculosis (CTB) only a fraction of this 10%. CTB is caused by mainly Mycobacterium tuberculosis and can lead to scarring and deformities. ... -
Formulation, in vitro release and transdermal diffusion of pravastatin by the implementation of the delivery gap principle
(2014)Active pharmaceutical ingredients (APIs), which are incorporated in different formulations, i.e. creams, gels, foams, etc., are applied to the skin for a therapeutic effect. This therapeutic effect could either be required ... -
Formulation, in vitro release and transdermal diffusion of salicylic acid and topical niacinamide
(North-West University, 2009)Acne affects as many as 80% of young adults and adolescents all over the world. This detrimental condition can be classified into four stages: (a) open comedo (blackhead), (b) closed comedo (whitehead), (c) papule and (d) ...