Browsing Health Sciences by Title
Now showing items 675-694 of 2060
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Evaluation of selected dye compounds as inhibitors of enzymes, relevant to neurological disorders
(North-West University (South-Africa), 2021)Neurological disorders such as Alzheimer’s disease, Parkinson’s disease and schizophrenia are disorders that affect a large part of the population, especially the elderly. The cause of these disorders is still not completely ... -
Evaluation of selected dye compounds as inhibitors of monoamine oxidase
(North-West University (South-Africa), 2019)Parkinson’s disease (PD) and Alzheimer’s disease (AD) are neurodegenerative diseases that significantly impact the quality of life of patients. The pathology of Parkinson’s disease is characterised by neuronal death of the ... -
Evaluation of surface sampling methods for platinum salts
(North-West University, 2010)Motivation: The health effects of platinum on the human body are a great concern. It affects the respiratory system as well as the skin. The demands for platinum have seemingly increased over the last few years due to its ... -
Evaluation of the effect of colloidal systems on biodistribution of selected prostate cancer radiopharmaceuticals
(North-West University (South-Africa), 2019)It has been reported that microemulsion (ME) delivery systems provide an opportunity to enhance the bioavailability and efficacy of a therapeutic agent whilst minimising side effects. The prostate-specific membrane antigen ... -
Evaluation of the effects of an instant soy and maize meal supplement on the vitamin A status of patients infected with the human immunodeficient virus
(North-West University (South-Africa), 2001)The development of a culture sensitive nutritional supplement for people infected with the human immunodeficiency virus (HIV) in developing countries needs to be investigated by experts in the area of nutrition and ... -
Evaluation of the effects of selected disintegrants on drug membrane permeation
(North-West University (South Africa) , Potchefstroom Campus, 2016)Virtually all solid dosage forms contain a disintegrating agent to help facilitate breakup, dissolution and absorption. Traditionally, excipients were thought to be pharmacologically inert, but recently, an increasing ... -
Evaluation of the efficacy of selected anticancer compounds in multidrug resistant cell culture models
(North-West University (South-Africa). Potchefstroom Campus, 2019)Small cell lung cancer (SCLC) has an aggressive disseminating nature and the relapse of cancer patients after initial treatment is common. Acquired multidrug resistance (MDR) can often be attributed to over-expression of ... -
An evaluation of the efficiency of various respiratory protective equipment, used within platinum processing
(2009)Workplace performance measurements of respiratory protective equipment (RPE) are fundamental to understanding how well users are protected during work activities. This study evaluated the effectiveness of various respiratory ... -
Evaluation of the enzyme inhibitory effect of carboxymethylated chitosan
(North-West University, 2003)Degradation of peroral administered drugs by various enzymes in the gastrointestinal tract has proven to be troublesome for the absorption' and bioavailability of protein and peptide drugs. Mucoadhesive polymers such as ... -
Evaluation of the fortification of sugar with vitamin A
(North-West University (South-Africa), 2001)Background, motivation and hypothesis: A high prevalence of micronutrient deficiencies has been described in the South African black population, especially vitamin A deficiency and iron deficiency anaemia (IDA). However, ... -
Evaluation of the in vitro antimicrobial activity of the Pheroid®-entrapped plant extract of Agapanthus africanus against human pathogens
(North-West University (South-Africa), 2019)Antimicrobial resistance is a major concern as existing antimicrobials are becoming less effective due to misuse and overuse (WHO, 2018b). Identifying novel compounds or treatments with a possible antimicrobial activity ... -
Evaluation of the in vitro biocompatibility of cortical bone matrix
(North-West University (South-Africa), 2022)Bone grafts play a critical role in the medical field, providing people the opportunity to recover from high impact trauma that caused serious complex fractures. Bone tissue engineering is a field that gained great interest ... -
Evaluation of the matrix-forming ability of chitosan through direct compression using a freely water-soluble drug
(North-West University, 2005)To utilise the direct compression method in this study was a very challenging task due to the physical powder properties of chitosan. The compressibility of chitosan was evaluated in the initial phase and the results ... -
Evaluation of the medicine procurement and supply management system in public hospitals in Lesotho
(2014)In a well-functioning medicine supply chain management system, procurement forms an integral part that needs to be closely monitored and integrated with other functions. Good procurement practices in the public health ... -
Evaluation of the methodology for determining the glycaemic index of foods with special reference to blood sampling
(North-West University, 2003)Different types of carbohydrates from different food sources affect blood glucose differently. This physiological effect of carbohydrate containing foods has been quantified and expressed as the glycaemic index (GI) of ... -
An evaluation of the necessity to use structured protocols to conduct forensic interviews
(North-West University, 2012)Child sexual abuse cases are particularly important in ensuring that victims and falsely accused individuals are protected and perpetrators are successfully convicted. Recent and continuing increases in the number of ... -
Evaluation of the oral delivery of goserelin with Pheroid® technology
(North-West University (South-Africa), 2019)The therapeutic amphiphilic peptide, goserelin, being investigated in these studies, is a type of hormone therapy generally used in addition to standard adjuvant therapy. Goserelin serves as treatment for numerous ... -
Evaluation of the pharmacovigilance system in the Dr Kenneth Kaunda District in the North West Province
(2015)The use of drugs is not without the risk of possible adverse drug reactions (ADRs). Information about ADRs is limited due to the short time frame and limited population groups in clinical trials. Pharmacovigilance is the ... -
Evaluation of the profile and standard of community pharmacy practice in Lesotho
(North-West University (South-Africa), 2021)The profession of pharmacy is growing fast and like in many countries, Lesotho has seen more growth in community pharmacy practice. The increased number of community pharmacies should be matched with necessary regulations, ... -
Evaluation of thermal desorption as an alternative technique for the measurement of coal tar pitch volatiles
(North-West University, 2011)Motivation: The accurate and reliable measurement of the concentration of coal tar pitch volatiles (CTPVs) in ambient air has proved to be a challenge for occupational hygienists. The challenge must however be confronted ...