Browsing Health Sciences by Subject "Bioavailability"
Now showing items 1-9 of 9
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The association between black tea consumption and iron status of African women in the North West Province : THUSA study
(North-West University, 2005)Motivation: A variety of factors including food shortage, poor hygiene and low education levels affects the nutritional status of black women. Women also have a high risk for the development of iron deficiency because ... -
A clinical investigation into the bioavailability of a peroral cannabinoid-Pheroid® formulation
(North-West University (South-Africa), 2020)The therapeutic advantages of pure Cannabidiol (CBD), a phytocannabinoid isolated from the Cannabis sativa L. plant, are emphasised by the growing use of CBD in numerous conditions ranging from supplementary to the treatment ... -
Development and formulation of an intranasal dosage form for cyclizine hydrochloride
(North-West University, 2004)A comprehensive review of the nasal route of administration, in particular the nasal drug delivery system has been presented. The physicochemical properties, mode of action and pharmacology of H1-receptor antagonists, in ... -
The effect of Pheroid® technology on the bioavailability of artemisone in primates
(2014)Malaria is one the world’s most devastating diseases. Several classes of drugs are used to treat malaria. Artemisinin combination therapy is the first line treatment of uncomplicated malaria. The artemisinin derivative, ... -
Efficacy enhancement of the antimalarial drugs, mefloquine and artesunate, with PheroidTM technology
(North-West University, 2010)Malaria is currently one of the most imperative parasitic diseases in developing countries. Artesunate has a short half-life, low aqueous solubility and resultant poor and erratic absorption upon oral administration, which ... -
The impact of PheroidTM technology on the bioavailability and efficacy of anti-tuberculosis drugs in an animal model
(North-West University, 2009)Tuberculosis (TB) is a worldwide pandemic with vast challenges in the fight against the disease. Challenges include the long and tedious treatment regimens and chemotherapy with adverse side effects. One approach in ... -
Pharmacokinetic interactions of Aloe vera gel polysaccharides with indinavir
(North-West University (South Africa) , Potchefstroom Campus, 2015)Aloe vera (L.) Burm.f. (Aloe barbadensis Miller) gel and whole leaf materials have shown the ability to modulate the bioavailability of vitamins and to change the transport of molecules across intestinal epithelia. In this ... -
The potential of fermentation and blanching in improving bioaccessibility and bioavailability of iron and zinc in African leafy vegetables
(North-West University (South-Africa), 2021)Introduction - Iron and zinc deficiencies remain a significant problem in sub-Saharan Africa. Consumption of African leafy vegetables (ALVs) have shown potential in alleviating these deficiencies. However, ALVs also ... -
Rifampicin raw materials complexities and approaches to address solubility and in vitro permeability
(North-West University (South-Africa), 2021)Tuberculosis is classified as a global emergency because it is taking lives at an alarming rate and developing countries with insufficient health care systems are primarily affected. Fixed dose combination drugs (FDCs) ...