Browsing Health Sciences by Subject "Glutamate"
Now showing items 1-3 of 3
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Investigating the role of the NO-cGMP pathway in an animal model of posttraumatic stress disorder (PTSD)
(North-West University, 2004)Posttraumatic stress disorder (PTSD) is a severe anxiety disorder characterised by hypothalamic-pituitary-adrenal (HPA)-axis abnormalities, hyperarousal, anxiety, flashbacks of trauma memories and avoidance. Increasing ... -
Regional neurochemical characterization of the flinders sensitive line rat with regard to gaba and cholinergic signalling pathways
(North-West University, 2008)Despite their acknowledged efficacy, currently available antidepressants still demonstrate undesirable side effects, shortfalls in effectiveness and a delayed onset of action. All these agents act via monoaminergic mechanisms, ... -
Tryptophan metabolism in the deer mouse and its response to serotonergic intervention
(North-West University (South-Africa), 2022)Obsessive-compulsive disorder (OCD)1 is a debilitating neuropsychiatric condition that notably infringes on an individual’s quality of life. The condition is characterised by two primary symptoms, namely obsessions (intrusive ...