Browsing Health Sciences by Subject "PheroidTM technology"
Now showing items 1-5 of 5
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Development of a stability indicating HPLC method for the Pheroid™ delivery system
(North-West University, 2010)Stability plays an important role in the development of a new drug product. High Performance Liquid Chromatography (HPLC) is considered a stability indicating method of analysis. It is widely used in the pharmaceutical ... -
Formulation, in vitro release and transdermal diffusion of acyclovir and ketoconazole for skin conditions in HIV/AIDS patients
(North-West University, 2009)The aim of this in vitro study was to investigate the efficacy of the novel Pheroid™ technology system in a semi-solid dosage form, for the topical delivery of acyclovir (5% w/w), an anti-viral agent and ketoconazole (2% ... -
In vitro antimalarial efficacy enhancement of selected antibiotics with PheroidTM technology
(North-West University, 2010)The Plasmodium falciparum parasite, carried by Anopheles mosquitoes, is currently a global problem due to the rising incidence of resistance of the parasite to available antimalaria drugs. Resistance and difficult treatment ... -
Novel artemisinin derivatives with PheroidTM technology for malaria treatment
(North-West University, 2009)Artemisinins are known for their low aqueous solubility and resultant poor and erratic absorption upon oral administration. The poor solubility and erratic absorption usually translate, to low bibavailability. Enzymatic ... -
Pharmaceutical applications of PheroidTM technology
(North-West University, 2009)For a drug to have a therapeutic effect, it has to reach its site of action in sufficient quantities. The Pheroid drug delivery system enhances the absorption of drugs in various pharmacological categories and is the focus ...