Browsing Health Sciences by Subject "Topical drug delivery"
Now showing items 1-6 of 6
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Comparative study of the topical delivery of selected female hormones
(North-West University (South-Africa), 2020)Intrinsic skin ageing is predominantly caused by a decrease in female hormones as menopause approaches. It is suggested that topical application of female hormones may treat these ageing symptoms. Unfortunately, the ... -
Formulation and topical delivery of a safflower oil nano-emulsion containing artemether
(North-West University (South Africa) , Potchefstroom Campus, 2016)Cutaneous tuberculosis (CTB), one of the forms of extra-pulmonary tuberculosis (TB), occurs 1.5% of the time when the Mycobacterium tuberculosis bacterium enters the skin, either through direct contact or through airborne ... -
Formulation of an emulgel for topical delivery of roxithromycin
(North-West University (South-Africa), 2020)The aim of this study was to establish whether liposomal or niosomal vesicle systems containing roxithromycin could be developed further into semi-solid formulations (emulgels) for topical delivery of the active pharmaceutical ... -
Investigation of the stabilising effects of niosomes on the amorphous forms of roxithromycin
(North-West University (South Africa), Potchefstroom Campus, 2018)The first aim of this research study was to determine the effect of the excipients used in the typical niosome preparation on the solid-state nature of three solid-state forms of roxithromycin. The second aim was to ascertain ... -
Stability of amorphous forms of roxithromycin when encapsulated in liposomes
(North-West University (South-Africa), 2019)Acne vulgaris is a common chronic inflammatory disease, which affects the pilosebaceous units in the dermal layer of the skin (Krautheim & Gollnick, 2004:398; Williams et al., 2012:361). Several factors are involved during ... -
Transdermal delivery of isoniazid and rifampicin by pheroid technology
(North-West University, 2007)The aim of this in vitro study was to investigate the feasibility of the transdermal delivery of isoniazid (INH) and rifampicin (RMP) by means of the novel PheroidTM technology system. The application of the latter is ...