Now showing items 1-2 of 2
Establishing three-dimensional cell culture models to measure biotransformation and toxicity
(North-West University, Potchefstroom Campus, 2018)
A great proportion of new chemical entities will be terminated from the clinical drug development pipeline as a result of deficiencies in drug absorption, distribution, biotransformation and elimination as well as potential ...
Impact of selected herbal products on intestinal epithelial permeation and metabolism of indinavir
Patients on anti-retroviral (ARV) drug treatment are sometimes simultaneously taking other prescribed drugs and/or over-the-counter drugs and/or herbal remedies. Pharmacokinetic drug-drug or herb-drug interactions can occur ...